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Dajana Vuckovic, PhD

Associate Professor and Concordia University Research Chair, Chemistry and Biochemistry
Director, Centre for Biological Applications of Mass Spectrometry


Dajana Vuckovic, PhD

Education

NSERC PDF (University of Toronto)
PhD (University of Waterloo)

PetroCanada Young Innovator Award
Photo credit: Concordia University
Vuckovic group
Photo credit: Concordia University

Teaching activities

Undergraduate courses

CHEM 218 - Introductory Analytical Chemistry II

CHEM 498U - Advanced Bioanalytical Chemistry

CHEM 498E - Mass Spectrometry in Metabolomics and Proteomics 

SCOL 350 - Biomarkers

Graduate courses

CHEM 610U - Advanced Bioanalytical Chemistry

CHEM 614 - Mass Spectrometry in Metabolomics and Proteomics



Publications

Global metabolomics

1.  Russo, M., Napylov, A., Paquet, A., Vuckovic, D., Comparison of N-ethyl maleimide and N-(1-phenylethyl) maleimide for derivatization of biological thiols using liquid chromatography-mass spectrometry, Anal. Bioanal. Chem. 412, 1639-1652, (2020).

2.  Sonnenberg, R., Naz, S., Cougnaud, L., Vuckovic, D., Comparison of underivatized silica and zwitterionic sulfobetaine hydrophilic interaction liquid chromatography stationary phases for global metabolomics of human plasma, J. Chromatogr. A, 1608, 460419, (2019).

3.  Vuckovic, D.  Improving metabolome coverage and data quality: advancing metabolomics and lipidomics for biomarker discovery, Chem. Comm, 54, 6728-6749 (2018, invited feature for Emerging Investigators Issue 2018).

4.  Sitnikov, D., Monnin, C. & Vuckovic D., Systematic Assessment of Seven Solvent and Solid-Phase Extraction Methods for Metabolomics Analysis of Human Plasma by LC-MS, Sci. Rep.6, 38885 (2016).


Mycotoxins

1.  Slobodchikova, I., Sivakumar, R., Md Rahman, S., Vuckovic, D. Characterization of phase I and glucuronide phase II metabolites of 17 mycotoxins using liquid chromatography – high-resolution mass spectrometry, Toxins, 11(8), 433; https://doi.org/10.3390/toxins11080433, (2019).

2.  Slobodchikova, I. & Vuckovic, D. Liquid chromatography – high-resolution mass spectrometry method for monitoring of 17 mycotoxins in human plasma for exposure studies, J. Chromatogr. A, 1548, 51-63 (2018).



Lipidomics

1. Napylov, A., Reyes Garces, N., Gomez-Rios, G., Monnin C., Olkowicz, M., Lendor, S., Bojko, B., Hamani, C., Pawliszyn, J., Vuckovic, D. (2020) In vivo solid-phase microextraction for sampling of oxylipins in brain of awake, moving rats, Angew. Chem. Int. Ed. 59, 2392-2398, (2020).

2.  Monnin, C., Ramrup, P., Daigle-Young, C. & Vuckovic D., Improving negative ESI-LC-MS lipidomic analysis of human plasma using acetic acid as a mobile phase additive, Rapid Commun. Mass Spectrom. 32:201-211 (2018, top 20 most-downloaded article of 2017-2018).

3. J.A. Bowden, A. Heckert, C.Z. Ulmer, C.M. Jones, J.P. Koelmel, L. Abdullah, … D. Vuckovic, J.M. Weir, R. Welti, M.R. Wenk, C. Wheelock, M. Yuan, X. H. Zhao, & S. Zhou, Harmonizing Lipidomics: NIST Interlaboratory Comparison Exercise for Lipidomics using Standard Reference Material 1950 – Metabolites in Frozen Human Plasma, J. Lipid Res. 58, 2275-2288 (2017). 

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