Shimon Amir, PhD

Shimon Amir received his PhD in Psychology from McGill University. After completing his postdoctoral training at the Center for Research on Drug Dependence, Concordia University, he joined the Department of Isotope Research and Neurobiology at the Weizmann Institute of Science, Rehovot, Israel, and was promoted to the rank of Associate Professor in 1986. In 1988 he joined the Department of Psychology and the Center for Studies in Behavioral Neurobiology at Concordia University and was promoted to the rank of Professor in 1991. He has served as Director of the Center for Studies in Behavioral Neurobiology from 2009-2019. He was elected to the Board of Governors of Concordia in 2007 and has served as Vice-Chairman of the Board from 2011-2016. He is a Fellow of the Royal Society of Canada, Academy of Science; Fellow of the American Association for the advancement of Science; Fellow of the Canadian College of Neuropsychopharmacology; Fellow of the Association of Psychological Science; Member of the Provost Circle of Distinction; Honorary Concordia University Research Chair; and Distinguished University Research Professor.

Funding

Canadian Institutes of Health Research (CIHR), Natural Sciences and Engineering Research Council of Canada (NSERC), Fonds Nature et Technologies Quebec (FRQNT), Concordia University

Lab members

Selected publications

• de Zavalia, N., Ferraro, S., and Amir, S. (2023). Sexually dimorphic role of circadian clock genes in alcohol drinking behavior. Psychopharmacology (Berl) 240, 431-440.

• Meyer, C., Schoettner, K., and Amir, S. (2022). The effects of circadian desynchronization on alcohol consumption and affective behavior during alcohol abstinence in female rats. Front Behav Neurosci 16, 1044783.

• Schoettner K., Alonso M., Button M., Goldfarb C., Herrera J., Quteishat N., Meyer C., Bergdahl A. and Amir S. (2022) Characterization of Affective Behaviors and Motor Functions in Mice with a Striatal-Specific Deletion of Bmal1and Per2. Front. Physiol. 13:922080. doi: 10.3389/fphys.2022.922080

• Ferraro, S, de Zavalia, N, Belforte, N, and Amir, S. (2021) In utero exposure to administration of valproic-acid alters circadian organization and clock-gene expression: Implications for Autism Spectrum Disorders. Frontiers in Behavioral Neuroscience. doi: 10.3389/fnbeh.2021.711549

• de Zavalia, N., Schoettner, K., Goldsmith, J.A., Solis, P., Ferrraro, S., Parent, G. and Amir, S. (2021). Bmal1 in the striatum influences alcohol intake in a sexually dimorphic manner. Commun Biol 4, 1227. https://doi.org/10.1038/s42003-021-02715-9

• Pathak.S, Liu,D., Li,T., Zheng, L., de Zavalia, N., Li, J., Ramanujam, K., Storch, K.-F.,Kaufman, R.J., Jin, V.X., Amir, S., Sonenberg, N., Cao, R. (2019) The eIF2α kinase GCN2 modulates period and rhythmicity of the circadian clock by translational control of Atf4, Neuron 104, 1-12. https://doi.org/10.1016/j.neuron.2019.08.007.

• Liu D, Stowie A, deZavalia N, Leise T, Pathak SS, Drewes LR, Davidson AJ, Amir S, Sonenberg N, Cao R (2018) mTOR signaling in VIP neurons regulates circadian clock synchrony and olfaction. Proc Natl Acad Sci USA 115, E3296-E3304. [PubMed] [Content]
• Hood S, Amir S (2018) Biological clocks and rhythms of anger and aggression. Front Behav Neurosci 12:4. [PubMed] [Content]
• Hood S, Amir S (2017) Neurodegeneration and the circadian clock. Front Aging Neurosci 9:170. [PubMed] [Content]
• Hood S, Amir S (2017) The aging clock: circadian rhythms and later life. J Clin Invest 127:437-446. [PubMed] [Content]
• Cao R, Gkogkas CG, deZavalia N, Blum ID, Yanagiya A, Tsukumo Y, Xu H, Lee C, Storch KF, Liu AC, Amir S, Sonenberg N (2015) Light-regulated translational control of circadian behavior by eIF4E phosphorylation. Nat Neurosci 18:855-862. [PubMed] [Content]
• Cao R, Robinson B, Xu H,Gkogkas C, Khoutorsky A, Alain T, Yanagiya A, Nevarko T, Liu AC, Amir S, Sonenberg N (2013) Translational control of entrainment and synchrony of the suprachiasmatic circadian clock by mTOR/4E-BP1 signaling. Neuron 79:712-724. [PubMed] [Content]
• Hood S, Cassidy P, Cossette MP, Weigl Y, Verwey M, Robinson B, Stewart J, Amir S (2010) Endogenous dopamine regulates the rhythm of expression of the clock protein PER2 in the rat dorsal striatum via daily activation of D2 dopamine receptors. J Neurosci 30:14046-14058. [PubMed] [Content]
• Amir S, Stewart J (2009) Motivational modulation of rhythms of the expression of the clock protein PER2 in the limbic forebrain. Biol Psychiatry 65:829-834. [PubMed] [Content]
• Perrin, J. S., Segall, L. A., Harbour, V. L., Woodside, B. and Amir, S. (2006) The expression of the clock protein PER2 in the limbic forebrain is modulated by the estrous cycle. Proc Natl Acad Sci U S A 103, 5591-6. 10.1073/pnas.0601310103 [PubMed] [Content]
• Lamont, E. W., Robinson, B., Stewart, J. and Amir, S. (2005) The central and basolateral nuclei of the amygdala exhibit opposite diurnal rhythms of expression of the clock protein Period2. Proc Natl Acad Sci U S A 102, 4180-4. 10.1073/pnas.0500901102 [PubMed] [Content]
• Amir, S., Lamont, E. W., Robinson, B. and Stewart, J. (2004) A circadian rhythm in the expression of PERIOD2 protein reveals a novel SCN-controlled oscillator in the oval nucleus of the bed nucleus of the stria terminalis. J Neurosci 24, 781-90.10.1523/JNEUROSCI.4488-03.2004 [PubMed] [Content]
• Amir, S. and Stewart, J. (1996) Resetting of the circadian clock by a conditioned stimulus. Nature 379, 542-5. 10.1038/379542a0 [PubMed] [Content]

Complete publication list

• de Zavalia, N., Ferraro, S., and Amir, S. (2023). Sexually dimorphic role of circadian clock genes in alcohol drinking behavior. Psychopharmacology (Berl) 240, 431-440.

• Schoettner, K., Alonso, M., Button, M., Goldfarb, C., Herrera, J., Quteishat, N., Meyer, C., Bergdahl, A., and Amir, S. (2022). Characterization of Affective Behaviors and Motor Functions in Mice With a Striatal-Specific Deletion of Bmal1 and Per2. Front Physiol 13, 922080.

• Meyer, C., Schoettner, K., and Amir, S. (2022). The effects of circadian desynchronization on alcohol consumption and affective behavior during alcohol abstinence in female rats. Front Behav Neurosci 16, 1044783.

• Nadeau, BG., Marchant, E.G., Amir, S. and Mistlberger, R.E. (2022) Thermoregulatory significance of immobility in the forced swim test. Physiology and Behavior 247: 113709. PMID 35065081 DOI: 10.1016/j.physbeh.2022.113709

• Ferraro, S., de Zavalia, N., Belforte, N., and Amir, S. (2021). In utero Exposure to Valproic-Acid Alters Circadian Organisation and Clock-Gene Expression: Implications for Autism Spectrum Disorders. Front Behav Neurosci 15, 711549.

• de Zavalia, N., Schoettner, K., Goldsmith, J.A., Solis, P., Ferrraro, S., Parent, G. and Amir, S. (2021). Bmal1 in the striatum influences alcohol intake in a sexually dimorphic manner. Commun Biol 4, 1227. https://doi.org/10.1038/s42003-021-02715-9

• Pathak.S, Liu,D., Li,T., Zheng, L., de Zavalia, N., Li, J., Ramanujam, K., Storch, K.-F.,Kaufman, R.J., Jin, V.X., Amir, S., Sonenberg, N., Cao, R. (2019) The eIF2α kinase GCN2 modulates period and rhythmicity of the circadian clock by translational control of Atf4, Neuron 104, 1-12. https://doi.org/10.1016/j.neuron.2019.08.007.
• Hood, S. and Amir, S. (2019) Sleep and aging: Circadian influences. Handbookof Behavioral Neuroscience 30, 651-664.
• Liu D, Stowie A, de Zavalia N, Leise T, Pathak SS, Drewes LR, Davidson AJ, Amir S, Sonenberg N, Cao R (2018) mTOR signaling in VIP neurons regulates circadian clock synchrony and olfaction. Proc Natl Acad Sci USA 115, E3296-E3304. [PubMed] [Content]
• Anyan J, Amir S (2018) Too depressed to swim or too afraid to stop? A reinterpretation of the forced swim test as a measure of anxiety-like behavior. Neuropsychopharmacology 43:931-933. [PubMed] [Content]
• Hood S, Amir S (2018) Biological clocks and rhythms of anger and aggression. Front Behav Neurosci 12:4. [PubMed] [Content]
• Pantazopoulos, H., Stork, O., Amir, S., and Gamble, K. (Editors) Circadian Rhythms in Regulation of Brain Processes and Role in Psychiatric Disorders, Neural Plasticity, 2018.
• Anyan J, Verwey M, Amir S (2017) Individual differences in circadian locomotor parameters correlate with anxiety- and depression-like behavior. PLoS One 12:e0181375. [PubMed][Content]
• Gavrila AM, Hood S, Robinson B, Amir S (2017) Effects of bilateral anterior agranular insula lesions on food anticipatory activity in rats. PLoS One 12:e0179370. [PubMed] [Content]
• Hood S, Amir S (2017) Neurodegeneration and the circadian clock. Front Aging Neurosci 9:170. [PubMed] [Content]
• Frederick A, Goldsmith J, de Zavalia N, Amir S (2017) Mapping the co-localization of the circadian proteins PER2 and BMAL1 with enkephalin and substance P throughout the rodent forebrain. PLoS One12:e0176279. [PubMed] [Content]
• Opiol H, de Zavalia N, Delorme T, Solis P, RutherfordS, Shalev U, Amir S (2017) Exploring the role of locomotor sensitization in the circadian food entrainment pathway. PLoS One12:e0174113. [PubMed] [Content]
• Hood S, Amir S (2017) The aging clock: circadian rhythms and later life. J Clin Invest 127:437-446. [PubMed] [Content]
• Verwey M, Dhir S, Amir S (2016) Circadian influences on dopamine circuits of the brain: regulation of striatal rhythms of clock gene expression and implications for psychopathology and disease. F1000Res5:2062. [PubMed] [Content]
• Verwey M, Amir S (2016) From genes to chronotypes: the influence of circadian clock genes on our daily patterns of sleep and wakefulness. Ann Transl Med 4:184. [PubMed] [Content]
• Waddington Lamont, E. and Amir, S. 2016. Circadian and ultradian clocks/rhythms. In: George Koob, Richard F Thompson and Michel Le Moal (eds.), Encyclopedia of Behavioral Neuroscience, Vol. 1, 257-261. Life Science Books, Academic Press, Elsevier Ltd., Oxford, UK
• Al-Safadi S, Branchaud M, Rutherford S, Amir S (2015) Glucocorticoids and stress-induced changes in the expression of PERIOD1 in the rat forebrain. PLoS One 10:e0130085. [PubMed] [Content]
• Verwey M, Al-Safadi S, Amir S (2015) Circadian rhythms and psychopathology: from models of depression to rhythms in clock gene expression and back again. Biol Psychiatry 78:220-221. [PubMed] [Content]
• Cao R, Gkogkas CG, de Zavalia N, Blum ID, Yanagiya A, Tsukumo Y,Xu H, Lee C, Storch KF, Liu AC, Amir S, Sonenberg N (2015) Light-regulated translational control of circadian behavior by eIF4E phosphorylation. Nat Neurosci 18:855-862. [PubMed] [Content]
• Al-Safadi S, Al-Safadi A, Branchaud M, Rutherford S, Dayanandan A, Robinson B, Amir S(2014) Stress-induced changes in the expression of the clock protein PERIOD1 in the rat limbic forebrain and hypothalamus: role of stress type, time of day, and predictability. PLoS One 9:e111166. [PubMed] [Content]
• Harbour VL, Weigl Y, Robinson B, Amir S (2014) Phase differences in expression of circadian clock genes in the central nucleus of the amygdala, dentate gyrus, and suprachiasmatic nucleus in the rat. PLoS ONE 9:e103309. [PubMed] [Content]
• Frederick A, Bourget-Murray J, Chapman CA, Amir S, Courtemanche R (2014) Diurnal influences on electrophysiological oscillations and coupling in the dorsal striatum and cerebellar cortex of the anesthetized rat. Front Syst Neurosci 8:145. [PubMed] [Content]
• Harbour VL, Weigl Y, Robinson B, Amir S (2013) Comprehensive mapping of regional expression of the clock protein PERIOD2 in rat forebrain across the 24-h day. PLoS ONE 8: e76391. [PubMed] [Content]
• Cao R, Robinson B, Xu H, Gkogkas C, Khoutorsky A, Alain T, Yanagiya A, Nevarko T, Liu AC, Amir S, Sonenberg N (2013) Translational control of entrainment and synchrony of the suprachiasmatic circadian clock by mTOR/4E-BP1 signaling. Neuron 79:712-724. [PubMed][Content]
• Weigl Y, Harbour VL, Robinson B, Dufresne L, AmirS (2013) Peripheral circadian clocks—a conserved phenotype? Chronobiol Int 30:559-576. [PubMed] [Content]
• Verwey M, Robinson B, Amir S (2013) Recording andanalysis of circadian rhythms in running-wheel activity in rodents. J Vis Exp71: e50186. [PubMed] [Content]
• Verwey M, Amir S (2012) Variable restricted feeding disrupts the daily oscillations of Period2 expression in the limbic forebrain and dorsal striatum in rats. J Mol Neurosci 46:258-264. [PubMed] [Content]
• Verwey M, Amir S (2011) Nucleus-specific effects of meal duration on daily profiles of Period1 and Period2 protein expression in rats housed under restricted feeding. Neuroscience 192:304-311.[PubMed] [Content]
• Hood S, Cassidy P, Mathewson S, Stewart J, Amir S (2011) Daily morphine injection and withdrawal disrupt 24-h wheel running and PERIOD2 expression patterns in the rat limbic forebrain. Neuroscience 186:65-75. [PubMed] [Content]
• Gravotta L, Gavrila AM, Hood S, Amir S (2011) Global depletion of dopamine using intracerebroventricular 6-hydroxydopamine injection disrupts normal circadian wheel-running patterns and PERIOD2 expression in therat forebrain. J Mol Neurosci 45:162–171. [PubMed] [Content]
• Harbour VL, Robinson B, Amir S (2011) Variations indaily expression of the circadian clock protein, PER2, in the rat limbic forebrain during stable entrainment to a long light cycle. J Mol Neurosci45:154–161. [PubMed] [Content]
• Hood S, Cassidy P, Cossette MP, Weigl Y, Verwey M, RobinsonB, Stewart J, Amir S (2010) Endogenous dopamine regulates the rhythm of expression of the clock protein PER2 in the rat dorsal striatum via daily activation of D2 dopamine receptors. J Neurosci 30:14046-14058. [PubMed] [Content]
• Segall LA, Amir S (2010) Exogenous corticosterone induces the expression of the clock protein, PERIOD2, in the oval nucleus of the bed nucleus of the stria terminalis and the central nucleus of the amygdala of adrenalectomized and intact rats. J Mol Neurosci 42:176-182. [PubMed][Content]
• Segall LA, Amir S (2010) Glucocorticoid regulation ofclock gene expression in the mammalian limbic forebrain. J Mol Neurosci42:168-175. [PubMed] [Content]
• Abizaid A, Amir S (2010) Eating and appetite. In I.P.Stolerman (ed.) Encyclopedia of Psychopharmacology, Part 5, 447-450,Springer. [Content]
• Lamont EW, Amir S (2010) Circadian and ultradian clocks/rhythms. In Koob G, Le Moal M, Thompson D (Eds.) Encyclopedia of Behavioral Neuroscience 1:257-261. London:Academic Press. [DOI]
• Verwey M, Amir S (2009) Food-entrainable circadian oscillators in the brain. Eur J Neurosci 30:1650-1657. [PubMed] [Content]
• Amir S, Stewart J (2009) Behavioral and hormonal regulation of expression of the clock protein, PER2, in the central extended amygdala. Prog Neuropsychopharmacol Biol Psychiatry 33:1321-1328.[PubMed] [Content]
• Waddington Lamont E, Amir S (2009) Masking. In Binder, M.D. Hirokawa, N., Windhorst, U., and Hirsch, M.C. (Eds.) Encyclopedia of Neuroscience. Springer Science, New York, pp 2241-2242. [Content]
• Segall LA, Milet A, Tronche F, Amir S (2009) Brain glucocorticoid receptors are necessary for the rhythmic expression of the clock protein, PERIOD2, in the central extended amygdala in mice. Neurosci Lett 457:58-60. [PubMed] [Content]
• Verwey M, Lam GY, Amir S (2009) Circadian rhythms of PERIOD1 expression in the dorsomedial hypothalamic nucleus in the absence of entrained food-anticipatory activity rhythms in rats. Eur J Neurosci 29:2217-2222. [PubMed] [Content]
• Amir S Stewart J (2009) Motivational modulation of rhythms of the expression of the clock protein PER2 in the limbic forebrain. Biol Psychiatry 65:829-834. [PubMed] [Content]
• Segall, L. A., Verwey, M. and Amir, S. (2008) Timed restricted feeding restores the rhythms of expression of the clock protein, Period2, in the oval nucleus of the bed nucleus of the stria terminalis andcentral nucleus of the amygdala in adrenalectomized rats. Neuroscience 157:52-6. 10.1016/j.neuroscience.2008.08.055 [PubMed] [Content]
• Verwey, M., Khoja, Z., Stewart, J. and Amir, S. (2008) Region-specific modulation of PER2 expression in the limbic forebrain and hypothalamus by nighttime restricted feeding in rats. Neurosci Lett 440: 54-8.10.1016/j.neulet.2008.05.043 [PubMed] [Content]
• Gavrila, A. M., Robinson, B., Hoy, J., Stewart, J., Bhargava,A. and Amir, S. (2008) Double-stranded RNA-mediated suppression of Period2 expression in the suprachiasmatic nucleus disrupts circadian locomotor activity in rats. Neuroscience 154: 409-14. 10.1016/j.neuroscience.2008.04.032 [PubMed] [Content]
• Rodaros, D., Caruana, D. A., Amir, S. and Stewart, J. (2007) Corticotropin-releasing factor projections from limbic forebrain and paraventricular nucleus of the hypothalamus to the region of the ventral tegmental area. Neuroscience 150:8-13. 10.1016/j.neuroscience.2007.09.043 [PubMed] [Content]
• Verwey, M., Khoja, Z.,Stewart, J. and Amir, S. (2007) Differential regulation of the expression of Period2 protein in the limbic forebrain and dorsomedial hypothalamus by daily limited access to highly palatable food in food-deprived and free-fed rats. Neuroscience 147: 277-85. 10.1016/j.neuroscience.2007.04.044 [PubMed] [Content]
• Waddington Lamont, E.,Harbour, V. L., Barry-Shaw, J., Renteria Diaz, L., Robinson, B., Stewart, J.and Amir, S. (2007) Restricted access to food, but not sucrose, saccharine, orsalt, synchronizes the expression of Period2 protein in the limbic forebrain. Neuroscience 144: 402-11. 10.1016/j.neuroscience.2006.09.027 [PubMed] [Content]
• Amir, S. and Robinson, B. (2006) Thyroidectomy alters the daily pattern of expression of the clock protein, PER2, in the oval nucleus of the bed nucleus of the stria terminalis and central nucleus of the amygdala in rats. Neurosci Lett 407: 254-7.10.1016/j.neulet.2006.08.057 [PubMed] [Content]
• Segall, L. A., Perrin,J. S., Walker, C. D., Stewart, J. and Amir, S. (2006) Glucocorticoid rhythms control the rhythm of expression of the clock protein, Period2, in oval nucleus of the bed nucleus of the stria terminalis and central nucleus of the amygdala in rats. Neuroscience 140, 753-7. 10.1016/j.neuroscience.2006.03.037 [PubMed] [Content]
• Perrin, J. S., Segall, L. A., Harbour, V.L., Woodside, B. and Amir, S. (2006) The expression of the clock protein PER2 in the limbic forebrain is modulated by the estrous cycle. Proc Natl Acad Sci U S A 103, 5591-6. 10.1073/pnas.0601310103 [PubMed] [Content]
• Amir, S., Harbour, V.L. and Robinson, B. (2006) Pinealectomy does not affect diurnal PER2 expression in the rat limbic forebrain. Neurosci Lett 399, 147-50.10.1016/j.neulet.2006.01.041 [PubMed] [Content]
• Lamont, E. W., Diaz, L.R., Barry-Shaw, J., Stewart, J. and Amir, S. (2005) Daily restricted feeding rescues a rhythm of period2 expression in the arrhythmic suprachiasmatic nucleus. Neuroscience 132, 245-8. 10.1016/j.neuroscience.2005.01.029 [PubMed] [Content]
• Lamont, E. W.,Robinson, B., Stewart, J. and Amir, S. (2005) The central and basolateral nuclei of the amygdala exhibit opposite diurnal rhythms of expression of the clock protein Period2. Proc Natl Acad Sci U S A 102, 4180-4.10.1073/pnas.0500901102 [PubMed] [Content]
• Beaule, C., Barry-Shaw, J. and Amir, S. (2004) Fos expression in the suprachiasmatic nucleus during photic entrainment of circadian rhythms in retinally damaged rats. J MolNeurosci 22, 223-30. 10.1385/JMN:22:3:223 [PubMed] [Content]
• Amir, S., Lamont, E.W., Robinson, B. and Stewart, J. (2004) A circadian rhythm in the expression of PERIOD2 protein reveals a novel SCN-controlled oscillator in the oval nucleus of the bed nucleus of the stria terminalis. J Neurosci 24, 781-90. 10.1523/JNEUROSCI.4488-03.2004 [PubMed] [Content]
• Beaule, C., Houle, L.M. and Amir, S. (2003) Expression profiles of PER2 immunoreactivity within the shell and core regions of the rat suprachiasmatic nucleus: lack of effect of photic entrainment and disruption by constant light. J Mol Neurosci 21, 133-47.10.1385/JMN:21:2:133 [PubMed] [Content]
• Beaule, C. and Amir, S.(2003) The eyes suppress a circadian rhythm of FOS expression in the suprachiasmatic nucleus in the absence of light. Neuroscience 121, 253-7. [PubMed] [Content]
• Beaule, C., Robinson,B., Lamont, E. W. and Amir, S. (2003) Melanopsin in the circadian timing system. J Mol Neurosci 21, 73-89. 10.1385/JMN:21:1:73 [PubMed] [Content]
• Popeski, N., Amir, S., Diorio, J. and Woodside, B. (2003) Prolactin and oxytocin interaction in the paraventricular and supraoptic nuclei: effects on oxytocin mRNA and nitric oxide synthase. J Neuroendocrinol 15, 687-96. [PubMed]
• Amir, S., Beaule, C., Arvanitogiannis, A. and Stewart, J. (2002) Modes of plasticity within the mammalian circadian system. Prog Brain Res 138, 191-203. [PubMed]
• Beaule, C. and Amir, S.(2002) Effect of 192 IgG-saporin on circadian activity rhythms, expression of P75 neurotrophin receptors, calbindin-D28K, and light-induced Fos in the suprachiasmatic nucleus in rats. Exp Neurol 176, 377-89. [PubMed] [Content]
• Beaule, C.,Arvanitogiannis, A. and Amir, S. (2001) Light suppresses Fos expression in the shell region of the suprachiasmatic nucleus at dusk and dawn: implications forphotic entrainment of circadian rhythms. Neuroscience 106, 249-54. [PubMed] [Content]
• Arvanitogiannis, A. and Amir, S. (2001) A novel, associative process modulating photic resetting of the circadian clock. Neuroscience 104, 615-8. [PubMed] [Content]
• Beaule, C. and Amir, S.(2001) Photic regulation of circadian rhythms and the expression of p75 neurotrophin receptor immunoreactivity in the suprachiasmatic nucleus in rats. Brain Res 894, 301-6. [PubMed] [Content]
• Arvanitogiannis, A.,Sullivan, J. and Amir, S. (2000) Time acts as a conditioned stimulus to control behavioral sensitization to amphetamine in rats. Neuroscience 101, 1-3. [PubMed] [Content]
• Arvanitogiannis, A., Robinson, B., Beaule, C. and Amir, S. (2000) Calbindin-D28k immunoreactivity in the suprachiasmatic nucleus and the circadian response to constant light in the rat. Neuroscience 99, 397-401. [PubMed] [Content]
• Arvanitogiannis, A., Stewart, J. and Amir, S. (2000) Conditioned stimulus control in the circadian system: two tales tell one story. J Biol Rhythms 15, 292-3; discussion 294-5.10.1177/074873000129001378 [PubMed] [Content]
• Funk, D. and Amir, S.(2000) Enhanced fos expression within the primary olfactory and limbic pathways induced by an aversive conditioned odor stimulus. Neuroscience 98, 403-6. [PubMed] [Content]
• Edelstein, K., Beaule, C., D'Abramo, R. and Amir, S. (2000) Expression profiles of JunB andc-Fos proteins in the rat circadian system. Brain Res 870, 54-65. [PubMed] [Content]
• Funk, D. and Amir, S.(2000) Circadian modulation of fos responses to odor of the red fox, a rodent predator, in the rat olfactory system. Brain Res 866, 262-7. [PubMed] [Content]
• Woodside, B. andAmir, S. Nitric oxide signaling in the hypothalamus, In Functional Neuroanatomy of the Nitric Oxide System, Handbook of Chemical Neuroanatomy (Eds., H.W.M. Steinbusch, J. de Vente, S.R. Vincent). Elsevier Science Ltd., Oxford, Vol. 17, 147-176, 2000.
• Arvanitogiannis, A. andAmir, S. (1999) Conditioned stimulus control in the rat circadian system depends on clock resetting during conditioning. Behav Neurosci 113, 1297-300. [PubMed]
• Funk, D. and Amir, S.(1999) Conditioned fear attenuates light-induced suppression of melatonin release in rats. Physiol Behav 67, 623-6. [PubMed] [Content]
• Amir, S., Cain, S., Sullivan, J., Robinson, B. and Stewart, J. (1999) In rats, odor-induced Fos in the olfactory pathways depends on the phase of the circadian clock. Neurosci Lett 272, 175-8. [PubMed] [Content]
• Amir, S., Cain, S., Sullivan, J., Robinson, B. and Stewart, J. (1999) Olfactory stimulation enhances light-induced phase shifts in free-running activity rhythms and Fos expression in the suprachiasmatic nucleus. Neuroscience 92, 1165-70. [PubMed] [Content]
• Goodwin, F. L., Amir, S. and Amit, Z. (1999) Environmental lighting has a selective influence on ethanol intake in rats. Physiol Behav 66, 323-8. [PubMed] [Content]
• Edelstein, K. and Amir, S. (1999) The intergeniculate leaflet does not mediate the disruptive effects of constant light on circadian rhythms in the rat. Neuroscience 90,1093-101. [PubMed] [Content]
• Amir, S. and Stewart, J. (1999) The effectiveness of light on the circadian clock is linked to its emotional value. Neuroscience 88, 339-45. [PubMed] [Content]
• Arvanitogiannis, A. and Amir, S. (1999) Resetting the rat circadian clock by ultra-short light flashes. Neurosci Lett 261, 159-62. [PubMed] [Content]
• Amir, S. and Stewart,J. (1999) Conditioned and unconditioned aversive stimuli enhance light-induced fos expression in the primary visual cortex. Neuroscience 89, 323-7. [PubMed] [Content]
• Beaule, C. and Amir, S.(1999) Photic entrainment and induction of immediate-early genes within the rat circadian system. Brain Res 821, 95-100. [PubMed] [Content]
• Popeski, N., Amir, S. and Woodside, B. (1999) Changes in NADPH-d staining in the paraventricular and supraoptic nuclei during pregnancy and lactation in rats: role of ovariansteroids and oxytocin. J Neuroendocrinol 11, 53-61. [PubMed]
• Amir, S. and Stewart,J. (1998) Conditioned fear suppresses light-induced resetting of the circadian clock. Neuroscience 86, 345-51. [PubMed] [Content]
• Edelstein, K. and Amir, S. (1999) The role of the intergeniculate leaflet in entrainment of circadian rhythms to a skeleton photoperiod. J Neurosci 19, 372-80. [PubMed] [Content]
• Edelstein, K. and Amir,S. (1998) Glutamatergic antagonists do not attenuate light-induced fos proteinin rat intergeniculate leaflet. Brain Res 810, 264-8. [PubMed] [Content]
• Amir, S. and Stewart, J. (1998) Conditioning in the circadian system. Chronobiol Int 15, 447-56. [PubMed]
• Amir, S., Robinson, B., Ratovitski, T., Rea, M. A., Stewart, J. and Simantov, R. (1998) A role for serotonin in the circadian system revealed by the distribution of serotonin transporter and light-induced Fos immunoreactivity in the suprachiasmatic nucleus and intergeniculate leaflet. Neuroscience 84, 1059-73. [PubMed] [Content]
• Amir, S. and Stewart,J. (1998) Induction of Fos expression in the circadian system by unsignaled light is attenuated as a result of previous experience with signaled light: arole for Pavlovian conditioning. Neuroscience 83, 657-61. [PubMed] [Content]
• Amir, S., Rackover, M. and Funk, D. (1997) Blockers of nitric oxide synthase inhibit stress activation of c-fos expression in neurons of the hypothalamic paraventricular nucleus in the rat. Neuroscience 77, 623-7. [PubMed] [Content]
• Woodside, B. and Amir, S. (1997) Lactation reduces Fos induction in the paraventricular and supraoptic nuclei of the hypothalamus after urethane administration in rats. Brain Res752, 319-23. [PubMed] [Content]
• Amir, S. and Edelstein,K. (1997) A blocker of nitric oxide synthase, NG-nitro-L-arginine methyl ester,attenuates light-induced Fos protein expression in rat suprachiasmatic nucleus. Neurosci Lett 224, 29-32. [PubMed] [Content]
• Woodside, B. and Amir, S. (1996) Reproductive state changes NADPH-diaphorase staining in the paraventricular and supraoptic nuclei of female rats. Brain Res 739,339-42. [PubMed] [Content]
• Edelstein, K. and Amir, S. (1996) Constant light induces persistent Fos expression in rat intergeniculate leaflet. Brain Res 731, 221-5. [PubMed] [Content]
• Amir, S. and Robinson,B. (1996) Fos expression in rat visual cortex induced by ocular input of ultraviolet light. Brain Res 716, 213-8. 10.1016/0006-8993(96)00025-X [PubMed] [Content]
• Amir, S. and Stewart,J. (1996) Resetting of the circadian clock by a conditioned stimulus. Nature379, 542-5. 10.1038/379542a0 [PubMed] [Content]
• Amir, S. and Robinson,B. (1995) Ultraviolet light entrains rodent suprachiasmatic nucleus pacemaker. Neuroscience 69, 1005-1011. [PubMed] [Content]
• Amir, S., Robinson, B. and Edelstein, K. (1995) Distribution of NADPH-diaphorase staining and light-induced Fos expression in the rat suprachiasmatic nucleus region supports a role for nitric oxide in the circadian system. Neuroscience 69, 545-55. [PubMed] [Content]
• Edelstein, K. and Amir,S. (1995) Non-photic manipulations induce expression of Fos protein in the suprachiasmatic nucleus and intergeniculate leaflet in the rat. Brain Res 690,254-8. [PubMed] [Content]
• Woodside, B., Robinson,B. and Amir, S. (1995) Induction of Fos protein in a model of closed head injury in rats. Brain Res 690, 48-54. [PubMed]
• Edelstein, K., Pfaus, J.G., Rusak, B. and Amir, S. (1995) Neonatal monosodium glutamate treatment prevents effects of constant light on circadian temperature rhythms of adult rats. Brain Res 675, 135-42. [PubMed] [Content]
• Rotzinger, S., Aragon, C. M., Rogan, F., Amir, S. and Amit, Z. (1995) The nitric oxide synthase inhibitor NW-nitro-L-arginine methylester attenuates brain catalase activity invitro. Life Sci 56, 1321-4. [PubMed] [Content]
• Amir, S. Nitric oxide signaling in the hypothalamus. In: Nitric Oxide in the Nervous System. S. R. Vincent (Ed.) Academic Press Limited, pp. 151-162, 1995.
• Amir, S., Robinson, B.and Woodside, B. (1994) Induction of Fos protein in the piriform cortex after brain injury in pentobarbital-anaesthetized rats: lack of effect of lactation. Brain Res 652, 341-5. [PubMed] [Content]
• Dib, B., Rompre, P. P.,Amir, S. and Shizgal, P. (1994) Thermogenesis in brown adipose tissue is activated by electrical stimulation of the rat dorsal raphe nucleus. Brain Res650, 149-52. [PubMed] [Content]
• Amir, S. (1994) N-Methyl-D-aspartate receptor-mediated signaling in the supraoptic nucleus involves activation of a nitric oxide-dependent pathway. Brain Res 645,330-4. [PubMed] [Content]
• Stewart, J., Deschamps, S. E. and Amir, S. (1994) Inhibition of nitric oxide synthase does not block the development of sensitization to the behavioral activating effects of amphetamine. Brain Res 641, 141-4. [PubMed] [Content]
• Bhatnagar, S., Meaney, M. J. and Amir, S. (1993) The effects of prostaglandin E2 injected into the paraventricular nucleus of the hypothalamus on brown adipose tissue thermogenesis in spontaneously hypertensive rats. Brain Res 613, 285-7. [PubMed] [Content]
• Amir, S. (1992) Blocking NMDA receptors or nitric oxide production disrupts light transmission to the suprachiasmatic nucleus. Brain Res 586, 336-9. [PubMed] [Content]
• Amir, S. and De Blasio,E. (1991) Activation of brown adipose tissue thermogenesis by chemical stimulation of the hypothalamic supraoptic nucleus. Brain Res 563, 349-52. [PubMed] [Content]
• Amir, S. and English, A. M. (1991) An inhibitor of nitric oxide production, NG-nitro-L-arginine-methyl ester, improves survival in anaphylactic shock. EurJ Pharmacol 203, 125-7. [PubMed] [Content]
• Amir, S., De Blasio, E. and English, A. M. (1991) NG-monomethyl-L-arginine co-injection attenuates the thermogenic and hyperthermic effects of E2 prostaglandin microinjection into the anterior hypothalamic preoptic area in rats. Brain Res 556, 157-60. [PubMed] [Content]
• Amir, S. (1990) Activation of brown adipose tissue thermogenesis by chemical stimulation of the posterior hypothalamus. Brain Res 534, 303-8. [PubMed] [Content]
• Dymshitz, J., Malach,R., Amir, S. and Simantov, R. (1990) Factors regulating the expression of acetylcholinesterase-containing neurons in striatal cultures: effects of chemical depolarization. Brain Res 532, 131-9. [PubMed] [Content]
• Amir, S. and Schiavetto, A. (1990) Injection of prostaglandin E2 into the anterior hypothalamic preoptic area activates brown adipose tissue thermogenesis in the rat. BrainRes 528, 138-42. [PubMed] [Content]
• Amir, S., Schiavetto, A. and Pollock, R. (1990) Insulin co-injection suppresses the thermogenic response to glutamate microinjection into the VMH in rats. Brain Res 527,326-9. [PubMed] [Content]
• Amir, S. (1990) Intra-ventromedial hypothalamic injection of glutamate stimulates brown adipose tissue thermogenesis in the rat. Brain Res 511, 341-4. [PubMed] [Content]
• Amir, S. (1990) Stimulation of the paraventricular nucleus with glutamate activates interscapular brown adipose tissue thermogenesis in rats. Brain Res 508,152-5. [PubMed] [Content]
• Amir, S. and Pollock, R. Counterregulation of stress-induced hyperglycemia by thyrotropin-releasing hormone. In:Psychobiology of Stress. A. Oliverio and S. Puglisi-Allegra (Eds.), Kluwer AcademicPublishers, pp. 143-150, 1990.
• Shechter, Y., Meyerovitch, J., Farfel, Z., Sack, J., Bruck, R., Bar-Meir, S., Amir, S.,Degani, H. and Karlish, S.J.D. Insulin mimetic effects of vanadium. In:Vanadium in Biological Systems. N. Dennis Chasteen (Ed.), Kluwer Academic Publishers, pp. 129-142, 1990.
• Amir, S. (1989) Retinohypothalamic tract stimulation activates thermogenesis in brown adipose tissue in the rat. Brain Res 503, 163-6. [PubMed] [Content]
• Amir, S., Shizgal, P.and Rompre, P. P. (1989) Glutamate injection into the suprachiasmatic nucleus stimulates brown fat thermogenesis in the rat. Brain Res 498, 140-4. [PubMed] [Content]
• Meyerovitch, J., Shechter, Y. and Amir, S. (1989) Vanadate stimulates in vivo glucose uptake in brain and arrests food intake and body weight gain in rats. Physiol Behav 45,1113-6. [PubMed] [Content]
• Amir, S., Lagiorgia, M.and Pollock, R. (1989) Intra-ventromedial hypothalamic injection of insulin suppresses brown fat thermogenesis in the anaesthetized rat. Brain Res 480,340-3. [PubMed] [Content]
• Amir, S., Pollock, R.and Lagiorgia, M. (1989) Intra-hypothalamic injection of thyrotropin-releasing hormone suppresses brown fat thermogenesis in the anaesthetized rat. Brain Res478, 361-4. [PubMed] [Content]
• Amir, S. and Shechter, Y. (1988) Glucose transport. Nature 336, 528. 10.1038/336528b0 [PubMed] [Content]
• Amir, S. (1988)Thyrotropin-releasing hormone (TRH): insulin-like action on glucoregulation. Biochem Pharmacol 37, 4245-51. [PubMed]
• Amir, S. and Jackson, I. M. (1988) Immunological blockade of endogenous thyrotropin-releasing hormone impairs recovery from hyperglycemia in mice. Brain Res 462, 160-2. [PubMed] [Content]
• Dymshitz, J. and Amir, S. (1988) Opposite effects of restraint on morphine analgesia andnaloxone-induced jumping. Pharmacol Biochem Behav 30, 905-10. [PubMed]
• Malcolm, D. S., Zaloga,G. P., Willey, S. C., Amir, S. and Holaday, J. W. (1988) Naloxone potentiates epinephrine's pressor actions in endotoxemic rats. Circ Shock 25, 259-65. [PubMed]
• Amir, S. (1988)Thyrotropin-releasing hormone (TRH) blocks glucagon-induced hyperglycemia in mice: dissociation of the antihyperglycemic and pituitary actions of TRH. BrainRes 455, 201-3. [PubMed] [Content]
• Amir, S. (1988) TPA(12-O-tetradecanoylphorbol-13-acetate) enhances the central hypoglycemic action of thyrotropin-releasing hormone in mice. Brain Res 450, 369-72. [PubMed] [Content]
• Amir, S. and Shechter,Y. (1988) Apparent involvement of protein kinase C in the central glucoregulatory action of insulin. Brain Res 450, 272-9. [PubMed] [Content]
• Shechter, Y., Meyerovitch, J. and Amir, S. (1988) The use of post-binding agents in studying insulin action and its relation to experimental diabetes. Biochem Pharmacol 37,1891-6. [PubMed]
• Amir, S. and Rivkind, A. I. (1988) Prevention of clonidine-stimulated hyperglycemia by thyrotropin-releasing hormone. Peptides 9, 527-31. [PubMed] [Content]
• Amir, S. (1988) Aging blocks the thermoregulatory action of thyrotropin-releasing hormone in anaesthetized rats. Brain Res 440, 181-4. [PubMed] [Content]
• Amir, S. and Butler, P.D. (1988) Thyrotropin-releasing hormone blocks neurally-mediated hyperglycemiathrough central action. Peptides 9, 31-5. [PubMed] [Content]
• Amir, S. (1988) Anaphylactic shock: catecholamine actions in the responses to opioid antagonists. Prog Clin Biol Res 264, 265-74. [PubMed]
• Amir, S., Harel, M. andRivkind, A. I. (1987) Thyrotropin-releasing hormone potently reverse sepinephrine-stimulated hyperglycemia in mice. Brain Res 435, 112-22. [PubMed] [Content]
• Amir, S., Meyerovitch,J. and Shechter, Y. (1987) Vanadate ions: central nervous system action on glucoregulation. Brain Res 419, 392-6. [PubMed] [Content]
• Amir, S. and Shechter,Y. (1987) Centrally mediated hypoglycemic effect of insulin: apparent involvement of specific insulin receptors. Brain Res 418, 152-6. [PubMed] [Content]
• Amir, S., Sasson, S., Kaiser, N., Meyerovitch, J. and Shechter, Y. (1987) Polymyxin B is an inhibitor of insulin-induced hypoglycemia in the whole animal model. Studies on the mode of inhibitory action. J Biol Chem 262, 6663-7. [PubMed] [Content]
• Amir, S. (1986) Catalepsy induced by body pinch: relation to stress-induced analgesia. Ann NY Acad Sci 467, 226-37. [PubMed] [Content]
• Amir, S. (1986) Endorphins contribute to the loss of glucose homeostasis in anaphylactic shock. NIDA Res Monogr 75, 375-8. [PubMed]
• Malcolm, D. S., Amir, S. and Holaday, J. W. (1986) Central glucagon antagonizes morphine- and stress-induced antinociception in the mouse. NIDA Res Monogr 75, 371-4. [PubMed]
• Amir, S. (1986) Central glucagon-induced hyperglycemia is mediated by combined activation of the adrenal medulla and sympathetic nerve endings. Physiol Behav 37, 563-6. [PubMed] [Content]
• Amir, S., Rivkind, A.I. and Harel, M. (1985) Central thyrotropin-releasing hormone elicits systemic hypoglycemia in mice. Brain Res 344, 387-91. [PubMed] [Content]
• Amir, S. and Harel, M. (1985) Systemic hypoglycemia following central injection of endotoxin in mice. Brain Res 339, 382-5. [PubMed] [Content]
• Amir, S. and Shechter,Y. (1985) Polymyxin B is a potent inhibitor of insulin hypoglycemia in mice.Eur J Pharmacol 110, 283-5. [PubMed]
• Amir, S. and van Ree,J. M. (1985) Beneficial effect of gamma-endorphin-type peptides in anaphylactic shock. Brain Res 329, 329-33. [PubMed] [Content]
• Drago, F., Amir,S., Continella, G., Concetta Alloro, M. and Scapagnini, U. Effects of endogenous hyperprolactinemia on adaptive responses to stress. In: Prolactin:Basic and Clinical Aspects, R.M. Macleod, M.O. Thorner and U. Scapagnini(Eds.), Fidia Research Series, Albano Terme, Vol. 1, pp. 609-614, 1985.
• Amir, S. (1984) Anti-anaphylactic action in the mouse of thyrotropin-releasing hormone (TRH) is mediated through beta 1-adrenoceptive effectors. Neurosci Lett 46, 127-30. [PubMed] [Content]
• Amir, S., Harel, M. and Schachar, A. (1984) Thyrotropin-releasing hormone (TRH) improves survival in anaphylactic shock: a central effect mediated by the sympatho-adrenomedullary beta-adrenoceptive system. Brain Res 298, 219-24. [PubMed] [Content]
• Amir, S. (1984) Naloxone improves, and morphine exacerbates, experimental shock induced by release of endogenous histamine by compound 48/80. Brain Res 297, 187-90. [PubMed] [Content]
• Drago, F. and Amir, S.(1984) Effects of hyperprolactinaemia on core temperature of the rat. Brain ResBull 12, 355-8. [PubMed]
• Amir, S. (1984) Opiate antagonists reverse the hypoactivity associated with systemic anaphylaxis in mice. Pharmacol Biochem Behav 20, 483-5. [PubMed]
• Amir, S. (1984) Beneficial effect of i.c.v. naloxone in anaphylactic shock is mediated through peripheral beta-adrenoceptive mechanisms. Brain Res 290, 191-4. [PubMed] [Content]
• Amir, S. (1983) Proanaphylactic action of morphine is mediated through a central cholinergic mechanism. Eur J Pharmacol 95, 117-9. [PubMed] [Content]
• Amir, S. (1983) Morphine exacerbates anaphylactic shock in mice by stimulating central opiate receptors. Neurosci Lett 40, 169-74. [PubMed] [Content]
• Amir, S. (1983) Antianaphylactic effect of naloxone in mice is mediated by increased central sympathetic outflow to sympathetic nerve endings and adrenal medulla. Brain Res274, 180-3. [PubMed] [Content]
• Amir, S. and Harel, M.(1983) Role of endorphins in endotoxin-induced hyperglycaemia in mice. Neuropharmacology 22, 1117-9. [PubMed]
• Simantov, R. and Amir,S. (1983) Regulation of opiate receptors in mouse brain: arcuate nuclear lesion induces receptor up-regulation and supersensitivity to opiates. Brain Res 262,168-71. [PubMed] [Content]
• Amir, S. and Harel, M.(1983) Endorphins in endotoxin-induced hyperglycemia in mice. Arch Toxicol Suppl 6, 261-5. [PubMed]
• Amir, S. and Davis, L.(1982) Protective effect of neonatal monosodium glutamate-induced arcuate nucleus lesions in anaphylactic shock. Eur J Pharmacol 84, 237-8. [PubMed]
• Amir, S. (1982) Opiate antagonists improve survival in anaphylactic shock. Eur J Pharmacol 80, 161-2. [PubMed] [Content]
• Amir, S. and Bernstein,M. (1982) Endogenous opioids interact in stress-induced hyperglycemia in mice. Physiol Behav 28, 575-7. [PubMed] [Content]
• Amir, S. (1982) Involvement of endogenous opioids with forced swimming-induced immobility in mice. Physiol Behav 28, 249-51. [PubMed] [Content]
• Ornstein, K. and Amir, S. (1981) Pinch-induced catalepsy in mice. J Comp Physiol Psychol 95,827-35. [PubMed]
• Amir, S. (1981) Effects of ACTH on pain responsiveness in mice: interaction with morphine. Neuropharmacology 20, 959-62. [PubMed]
• Amir, S. (1981) Behavioral response of the genetically obese (ob/ob) mouse to heat stress: effects of naloxone and prior exposure to immobilization stress. Physiol Behav27, 249-53. [PubMed] [Content]
• Amir, S. and Simantov, R. (1981) Chronic lithium administration alters the interaction between opiate antagonists and opiate receptors in vivo. Neuropharmacology 20, 587-91. [PubMed]
• Amir, S., Brown, Z. W., Amit, Z. and Ornstein, K. (1981) Body pinch induces long lasting cataleptic like immobility in mice: behavioral characterization and the effect ofnaloxone. Life Sci 28, 1189-94. [PubMed]
• Amir, S., Amit, Z. and Brown, Z. W. (1981) A simple and adjustable restraining apparatus for mice. Physiol Behav 26, 335-6. [PubMed] [Content]
• Amir, S., Amit, Z. and Brown, Z. W. (1981) Stress, endorphins and psychosis. A hypothesis. Mod Probl Pharmacopsychiatry 17, 192-201. [PubMed]
• Amir, S., Galina, Z.H., Blair, R., Brown, Z. W. and Amit, Z. (1980) Opiate receptors may mediate the suppressive but not the excitatory action of ACTH on motor activity in rats. Eur J Pharmacol 66, 307-13. [PubMed]
• Amit, Z., Brown, Z. W.,Rockman, G. E., Smith, B. and Amir, S. (1980) Acetaldehyde: a positive reinforcer mediating ethanol consumption. Adv Exp Med Biol 126, 413-23. [PubMed]
• Amir, S., Brown, Z. W.and Amit, Z. (1980) The role of endorphins in stress: evidence and speculations. Neurosci Biobehav Rev 4, 77-86. [PubMed] [Content]
• Amit, Z., Brown, Z.W., Amir, S., Sutherland, E.A. and Smith, B. Behavioral assessment of the role of acetaldehyde in mediation of alcohol intake in animals and humans. In: Animal Models in Alcohol Research, K. Eriksson, J.D. Sinclair and K. Kiianmaa (Eds.),Academic Press, London, pp. 159-165, 1980.
• Amir, S., Galina, H.Z. and Amit, Z. (1979) Chronic naltrexone administration reverses the suppressive effect of crowding on body weight gain in rats. Neuropharmacology 18,905-7. [PubMed]
• Amir, S. and Amit, Z.(1979) Enhanced analgesic effects of stress following chronic administration of naltrexone in rats. Eur J Pharmacol 59, 137-40. [PubMed] [Content]
• Amir, S., Blair, R. and Amit, Z. (1979) Increased amphetamine potency following chronic naltrexone administration in rats. Life Sci 25, 1407-12. [PubMed]
• Amir, S., Blair, R., Shizgal, P. and Amit, Z. (1979) Dual mechanism mediating opiate effects? Science 205, 424-5. 10.1126/science.205.4404.424 [PubMed] [Content]
• Amir, S., Solomon, M. and Amit, Z. (1979) The effect of acute and chronic naloxone administration on motoractivation in the rat. Neuropharmacology 18, 171-3. [PubMed]
• Amir, S. and Amit, Z. (1979) The pituitary gland mediates acute and chronic pain responsiveness instressed and non-stressed rats. Life Sci 24, 439-48. [PubMed]
• Amir, S. and Amit, Z. (1978) Endogenous opioid ligands may mediate stress-induced changes in the affective properties of pain related behavior in rats. Life Sci 23,1143-51. [PubMed]
• Amir, S. (1978) Brain aldehyde dehydrogenase: adaptive increase following prolonged ethanol administration in rats. Neuropharmacology 17, 463-7. [PubMed]
• Amir, S. and Stern, M.H. (1978) Electrical stimulation and lesions of the medial forebrain bundle of the rat: changes in voluntary ethanol consumption and brain aldehyde dehydrogenase activity. Psychopharmacology (Berl) 57, 167-74. [PubMed]
• Amir, S. (1978) Brain and liver aldehyde dehydrogenase activity and voluntary ethanol consumption by rats: relations to strain, sex, and age. Psychopharmacology (Berl) 57,97-102. [PubMed]
• Amir, S. (1977) Brain and liver aldehyde dehydrogenase: relations to ethanol consumption in Wistar rats. Neuropharmacology 16, 781-4. [PubMed]
• Amit, Z., Corcoran, M.E., Amir, S. and Urca, G. (1973) Ventral hypothalamic lesions block the consumption of morphine in rats. Life Sci 13, 805-16. [PubMed]
• Amit, Z., Amir, S. andCorcoran, M. E. (1973) A possible artifact in studies of alcohol consumption in rats. Q J Stud Alcohol 34, 524-7. [PubMed]