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Faculty

Dr. Christopher L Brett, PhD

Professor, Biology
Co-Director, Centre for Microscopy at Concordia
Concordia University Research Chair in Applied Cell Science


Dr. Christopher L Brett, PhD
©Concordia University, photo by Lisa Graves

Education

PhD (Johns Hopkins University)
PDF (University of Washington)

Awards

University Research Fellow, 2019
Dean's Award for Excellence in Scholarship, 2019
Distinguished Alumnus Lecture, Johns Hopkins University (Baltimore, USA), 2019
Canada Research Chair Tier 2, 2011-2016

Research interests

Cell biology, synthetic biology, microscopy, lysosomes, extracellular vesicles, membrane trafficking, membrane fusion, nutrient transport, aging, cancer, Alzheimer's disease

*I am currently recruiting graduate (MSc, PhD) and undergrad (BSc Honours thesis, MITACS, USRA) students.

I am a cell physiologist and my research lab uses genetics, biochemistry, advanced microscopy and synthetic biology to study: (1) fundamental lysosome biology in health and disease, and (2) extracellular vesicles as novel therapeutics.

Whether they know it or not, everyone recycles. This is because every one of the billions of cells that make up you and I constantly recycle biomaterials using specialized tiny organelles called lysosomes. Lysosomes are an essential source of nutrients for cells and breakdown toxic biomaterials that accumulate as cells age. My lab uses baker's yeast (S. cerevisiae) and its vacuolar lysosome as models to study the molecular mechanisms underlying fundamental lysosome biology and how they promote longevity or contribute to age-related diseases.

Extracellular vesicles are tiny packages shared by all eukaryotic cells (from yeast to human) that mediate intercellular communication underlying diverse physiology, from immune responses to tissue development, suggesting they have enormous therapeutic potential. My group is using baker's yeast as a platform to engineer humanized yeast extracellular vesicles to hijack these processes with the aim of developing new therapeutic applications.


Publications

Education

B.A. Sociologie, UQAM
M.A. Sociologie, UQAM
Ph.D. Université de Paris-X, Nanterre

Research interests

Daniel Dagenais is member of the Collectif Société and on the editorial board of the journal Cahiers Société (a journal and research group founded by the late Michel Freitag). My work can be divided into three domains of reflection: a strong concern for social theory, namely the meaning of the renewal of sociological theory from the 1980s onwards (he edited: Hannah Arendt, le totalitarisme et le monde contemporain, PUL, 2003), including theories of identity. I am also concerned with the transformation of the family institution (see my book, The (Un)Making of the Modern Family, UBC Press, 2007).My research also focuses on contemporary suicide (centrally, youth suicide). This brought me to try and distinguish, more theoretically, historical semantics of suicide from the Ancient world to the present. I teach Introduction to society, Contemporary sociological theory, The Family, and the Sociology of suicide.


Research activities

SOCI 203; SOCI 402; SOCI 434; SOCI/ANTH 378

Introduction to Society
Contemporary Sociological Theory
Sociology of Suicide
Sociology/Anthropology of the Family

 


Teaching activities

My most recent publications include


Dagenais Daniel(dir). La liberté à l’épreuve de l’histoire. La critique du libéralisme chez Michel Freitag, Montréal, Liber,2017. (Actes du colloque international tenu à Montréal en novembre 2014).

Dagenais, Daniel et Gilles Gagné (dir): La sociologie de Michel Freitag, Montréal, Nota Bene, 2014.

Dagenais,Daniel, The (Un)Making of the Modern Family, translated by Jane Brierley, with an Afterword to English edition,Vancouver, UBC Press, 2008.

Daniel Dagenais : « La matrice de la théorie sociologique contemporaine », in Cahiers de recherche du Groupe interuniversitaire d’étude de la postmodernité, 3 mai 2019, p. 1-33.

Daniel Dagenais : « La prohibition de l’inceste revisitée », in Anthropologie et Sociétés, vol. 41, no.2, 2017, p. 275-298.

Dagenais, Daniel (2011): « Le suicide des jeunes : une pathologie du devenir adulte contemporain », in Recherches sociographiques, vol. LII, no. 1, p. 71-104.

Daniel Dagenais : « Liberté et identité », in Daniel Dagenais (Ed): La liberté à l’épreuve de l’histoire. La critique du libéralisme chez Michel Freitag, Montréal, Liber, 2017, p.287-315.

Dagenais, Daniel et Gilles Gagné (2014) : « L’œuvre de Michel Freitag dans la sociologie contemporaine », in Daniel Dagenais et Gilles Gagné (dir) : La sociologie de Michel Freitag, Montréal, Éditions Nota Bene, p. 5-32.

Dagenais, Daniel (2014): « Reprendre la question du genre, au lieu de défaire le genre », in Marc Chevrier et Camille Froidevaux-Metterie : Des hommes et des femmes singuliers. Perspectives croisées sur le devenir sexué des individus en démocratie, Paris, Armand Colin,2014, p. 83-109.


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