Paul Joyce, PhD
Professor, Chemistry and Biochemistry
Associate Dean, Academic Programs, Dean of Arts & Science (Office)
Ph.D. (Dalhousie University)
Biochemistry, Genomics, Proteomics, Molecular/Cell Biology.
My primary teaching interest is in biochemistry. I regularly teach Biochemistry I (CHEM271) and Biochemistry II (CHEM375). Biochemistry I is an introductory course and covers the basics of biochemistry including enzymology, protein structure and metabolism. Biochemistry II covers more of the specific biochemical reactions involved in metabolic pathways. I also teach Discovering Biotechnology (CHEM209) which is an introduction to the world of biotechnology for non-scientists. This course covers topics such as cloning and genetic engineering and includes discussions of the societal and ethical issues that are involved. In the past few years I have also taught graduate courses in Protein Targeting and Membrane Biochemistry.
Chakraborty PK, Schmitz-Abe K, Kennedy EK, Mamady H, Naas T, Durie D, CampagnaDR, Lau A, Sendamarai AK, Wiseman DH, May A, Jolles S, Connor P, Powell C,Heeney MM, Giardina PJ, Klaassen RJ, Kannengiesser C, Thuret I, Thompson AA,Marques L, Hughes S, Bonney DK, Bottomley SS, Wynn RF, Laxer RM, Minniti CP,Moppett J, Bordon V, Geraghty M, Joyce PBM, Markianos K, Rudner AM, Holcik M,Fleming MD (2014) Mutations in TRNT1, encoding the CCA-adding enzyme, causecongenital sideroblastic anemia with B cell immunodeficiency, periodic feversand developmental delay (SIFD). Blood 124:2867-2871.
Goring ME, Leibovitch M, Gea-Mallorqui E, Karls S, Richard F,Hanic-Joyce PJ, Joyce PBM (2013) The ability of anarginine to tryptophan substitution in Saccharomyces cerevisiae tRNAnucleotidyltransferase to alleviate a temperature-sensitive phenotype suggestsa role for motif C in active site organization. Biochim Biophys Acta. 1834:2097-2106.
Leibovitch M, Bublak D, Hanic-JoycePJ, Tillmann B, Flinner N, Amsel D, Scharf KD, Mirus O, Joyce PBM, Schleiff E (2013) The folding capacity of the maturedomain of the dual-targeted plant tRNA nucleotidyltransferase influencesorganelle selection. Biochem J. 453:401-412.
Kornblatt MJ, Richard Albert J, Mattie S, Zakaib J, Dayanandan S, Hanic-Joyce PJ, Joyce PBM (2013) The Saccharomycescerevisiae enolase-related regions encode proteins that are activeenolases. Yeast 30:55-69.
Abdolhosseini M, Sotsky JB, Shelar AP, Joyce PBM, Gorr S-U (2012) Human parotidsecretory protein is a lipopolysacchaide-binding protein: identification of ananti-inflammatory peptide domain. Mol.Cell. Biochem. 359:1-8. DOI10.1007/s11010-011-0991-2
My students in bold