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Catherine Bachewich, PhD

Affiliate Associate Professor, Biology



Glory, A.,Oostende, C., Geitmann, A and Bachewich,C. (2017). Depletion of the mitotic kinase Cdc5p in Candida albicans results in the formation of elongated buds that switchto the hyphal fate over time in a Ume6p and Hgc1p-dependentmanner.   Fungal Genet Biol. 2017 Aug 10;107:51-66. doi: 10.1016/j.fgb.2017.08.002 

Mogilevsky, K.*, Glory, A.* and Bachewich, C. 2012. The polo-like kinase PLKA in Aspergillus nidulans is not essential, but plays important roles in vegetative growth and negatively regulates sexual development. Eukaryotic Cell 11, 194-205.

Chou, H., Glory, A. and Bachewich, C. (2011). Orthologues of the APC/C coactivators Cdc20p and Cdh1p are important for mitotic progression and morphogenesis in Candida albicans. Eukaryotic Cell 10, 696-709.
Hussein, B., Huang, H., Glory, A., Osmani, A., Kaminskyj, S., Nantel, A. and Bachewich, C. (2011). G1/S transcription factor orthologues Swi4p and Swi6p are important but not essential for cell proliferation and influence hyphal development in the fungal pathogen Candida albicans. Eukaryotic Cell 10, 384-397.

Xu D, Jiang B, Ketela T, Lemieux S, Veillette K, Martel N, Davison J, Sillaots S, Trosok S, Bachewich C, Bussey H, Youngman P, Roemer T . 2007. Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans. PloS Pathog. 3, e92.

Whiteway M, Bachewich C. 2007. Morphogenesis in Candida albicans. Annu Rev Microbiol. 61: 529-553.

Whiteway, M. and Bachewich, C. 2006. Signal transduction in the interactions of fungal pathogens and mammalian hosts, in Molecular Principles of Fungal Pathogens, J. Heitman, S.Fuller, J. Edwards and A. Mitchell, Ed. ASM Press, 143-162.

Braun BR, van Het Hoog M, d'Enfert C, Martchenko M, Dungan J, Kuo A, Inglis, DO, Uhl MA, Hogues H, Berriman M, Lorenz M, Levitin A, Oberholzer U, Bachewich,C, Harcus D, Marcil A, Dignard D, Iouk T, Zito R, Frangeul L, Tekaia F, Rutherford K, Wang E, Munro CA, Bates S, Gow NA, Hoyer LL, Kohler G, Morschhauser J, Newport G, Znaidi S, Raymond M, Turcotte B, Sherlock G, Costanzo, M, Ihmels J, Berman J, Sanglard D, Agabian N, Mitchell AP, Johnson AD, Whiteway,M, Nantel A. 2005. A human-curated annotation of the Candida albicans genome. PLoS Genet.1:36-57.

Bachewich C, Nantel A, Whiteway M. 2005. Cell cycle arrest during S or M phase generates polarized growth via distinct signals in Candida albicans. Molecular Microbiolology 57:942-59

Bachewich C, Masker K, Osmani S. 2005. The polo-like kinase PLKA is required for initiation and progression throughmitosis in the filamentous fungus Aspergillus nidulans. Molecular Microbiology 55:572-87.

Bachewich, C. and Whiteway, M. 2005. Cyclin Cln3p links G1 progression to hyphal and pseudohyphal development in C. albicans. Eukaryotic Cell 4:95-102

Bachewich, C. Masker, K. and Osmani, S. 2005. The polo-like kinase PLKA is required for mitotic initiation and progression in the filamentous fungus Aspergillus nidulans. Molecular Microbiology 55: 572-587.

Davies, J., Osmani, A., De Souza C.P.C., Bachewich, C. and Osmani, S. 2005. A potential link between the NIMA mitotic kinase and nuclear membrane fission during mitotic exit in Aspergillus nidulans. Eukaryotic Cell 3: 1433-1444.

Bachewich, C., Thomas, D. and Whiteway, M. 2003. Depletion of a polo-like kinase in Candida albicans activates cyclase-dependent hyphal-like growth. Molecular Biology of the Cell 14, 2163-2180.


Selected publications

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