Sylvia Santosa, PhD, RD (CDO)
Associate Professor, Exercise Science
Canada Research Chair Tier II, Clinical Nutrition
Postdoctoral Fellowship, Mayo Clinic
PhD Nutritional Science, McGill University
RD, Member of the College of Dietitians of Ontario
BASc (Honours), Applied Human Nutrition, University of Guelph
Weight is a concern of millions of Canadians both on an individual and societal level. Despite existing public policy and individual weight interventions, we are still “growing” as a population with more Canadians overweight than not.
The metabolic and cellular mechanisms of why some overweight individuals develop diseases while others do not are not fully understood. Furthermore, in people with diseases, such as cardiovascular disease and diabetes, we do not fully understand how obesity affects the progression or treatment. Obesity treatment itself remains ineffective as most people who lose weight eventually gain it back.
The goal of Dr. Santosa’s research program is to identify the long-term effects of obesity, from the cell to the entire body. Her research applies techniques in biology, physiology and nutrition to study the effects of obesity that contribute to weight gain and disease.
Results will promote the development of better public health interventions from disease prevention to management.
Associate Researcher, Sacre Coeur Hospital
Editorial Board Member, Scientific Reports
Canadian Nutrition Society
College of Dietitians of Ontario
The Obesity Society
Canadian Obesity Network
Société Québécoise de Lipidologie, de Nutrition, et de Metabolisme
Réseau de Recherche en Santé Cardiométabolique, Diabète, et Obésité
Nutrition in Sports and Exercise
Varady KA*, Dam V*, Horne M, Cruz R, Klempel MC, Kroeger CM, Santosa S. Effects of weight loss viahigh fat vs low fat alternate day fasting diets on free fatty acid profiles.Scientific Reports. 2015:5;7561
Santosa S§, Jensen MD. Sex and sexsteroids: impact on the kinetics of fatty acids underlying body shape. HormoneMolecular Biology and Clinical Investigation. 2014:20;15-23
Santosa S, Swain J, Tchkonia T,Kirkland JL, Jensen MD. Inflammatory characteristics of adipose tissuecollected by surgical excision vs. needle aspiration. International Journal ofObesity. 2014: October epub ahead ofprint
Du S, Rajjo T, Santosa S,Jensen MD. The thermic effect of food is reduced in older adults. Hormone andMetabolic Research. 2014:46;365-9.
Santosa S, Jensen MD. AdipocyteFatty Acid Storage Factors Enhance Subcutaneous Fat Storage in PostmenopausalWomen. Diabetes. 2013:62;775-82.
Santosa S, Jensen MD. Effect ofMale Hypogonadism on Regional Adipose Tissue Fatty Acid Storage and LipogenicProteins. Public Library of Science One. 2012:7;e31473 (10 pages).Please see CV for complete list of publications.