Our interdisciplinary group, situated within both the Department of Physics and Biology at Concordia University, works on the development of an image-guided, targeted drug/gene delivery platform using biomedical ultrasound for the treatment of cardiovascular disease and cancer. This involves using focused ultrasound and acoustically-sensitive agents to spatially and temporally target therapeutic delivery to regions of disease. We use physical, biological, mathematical and engineering-based approaches to address major research themes:
- Physics of acoustically-sensitive microbubbles and droplets,
- Physical acoustics that initiate safe, transient sonoporation,
- Cellular repair mechanisms and their associated time-course and
- Key signaling molecules that initiate, sustain and reverse membrane permeability.