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Wilds Research Group

Wilds Research Group

TEACHING

Professor Christopher Wilds obtained his PhD in 2000 in organic chemistry from McGill University under the supervision of Professor Masad Damha working on the synthesis of 2’-fluoro-arabino nucleic acids and their investigation as antisense therapeutics. 

He pursued post-doctoral studies in the field of nucleic acid structure and DNA repair with Professor Martin Egli (Northwestern University and Vanderbilt University) and Professor Paul Miller (Johns Hopkins University).

He was hired as an Assistant Professor in the Department of Chemistry and Biochemistry at Concordia University in 2003. In 2008 was awarded tenure and promoted to the rank of Associate Professor. In 2019 he was promoted to Professor.

CHEM 222:  Introductory Organic Chemistry II (3 credits)

Prerequisite: CHEM 221. Introduction to the use of IR and NMR spectroscopy for the identification of simple organic compounds. Benzene and aromatic compounds: aromaticity, electrophilic aromatic substitution, nucleophilic aromatic substitution, substituent effects. Chemistry of aldehydes and ketones: nucleophilic addition, oxidation, reduction, and condensation reactions, tautomerism. Chemistry of carboxylic acids and their derivatives. Chemistry of alcohols, ethers, and related compounds. Amines: basicity, reac­tions. Lectures and laboratory.

CHEM 271:  Biochemistry I (3 credits)

Prerequisite: CHEM 221. An introduction to the essentials of biochemistry: protein structure, enzymology, carbohydrate metabolism, electron transport, integration and regulation of metabolism. Lectures, tutorials and laboratory.

CHEM 425/625: Nucleic Acid Chemistry (3 credits)

Prerequisite: CHEM 222, 271. This course introduces students to various topics in nucleic acid chemistry. The topics include nomenclature, structure and function of RNA and DNA; techniques and methods to investigate nucleic acid structure; DNA damage and repair; interaction of small molecules and proteins with nucleic acid; oligonucleotide‑based therapeutics (antisense, antigene, RNAi); synthesis of purines, pyrimidines and nucleosides; and solid‑phase oligonucleotide synthesis. Lectures only.

CHEM 472: Chemical Toxicology (3 credits)

Prerequisite: CHEM 222, 271. Introduction to the general principles of toxicology with emphasis on the toxic effects of chemicals in humans. Dose‑response relationship, types and routes of exposure, absorption and disposition of toxic substances, toxicokinetics, types of toxic response, and factors affecting toxic response. Toxicity testing, risk assessment, and interpretation of toxicological data. Lectures only.

SCOL 360N:  What is Life?  (3 credits)

This course explores a number of topics pertaining to the definitions and origin of life in addition to various experiments and techniques that are used in this multidisciplinary endeavor. These various concepts will be addressed through classroom discussions of material presented from various scholarly journals.  Lectures only.

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