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Thesis defences

PhD Oral Exam - Faisal Al-Yawer, Psychology

Auditory-cognitive associations in older adults: Differential effects of sex, test modality, and hearing measures

DATE & TIME
Monday, June 13, 2022 (all day)
COST

This event is free

ORGANIZATION

School of Graduate Studies

CONTACT

Daniela Ferrer

WHERE

Online

When studying for a doctoral degree (PhD), candidates submit a thesis that provides a critical review of the current state of knowledge of the thesis subject as well as the student’s own contributions to the subject. The distinguishing criterion of doctoral graduate research is a significant and original contribution to knowledge.

Once accepted, the candidate presents the thesis orally. This oral exam is open to the public.

Abstract

This dissertation presents findings that address auditory-cognitive associations in older adults with hearing loss (HL), particularly with regards to sex-related differences in said associations. Manuscript I (Chapter 2) reports the psychometric properties of the Montreal Cognitive Assessment scale (MoCA) when hearing-related items are excluded from scoring (MoCA-Modified). This involved a cross-sectional analysis of the original MoCA validation study data in healthy older adults, older adults with mild cognitive impairment (MCI), and older adults with mild Alzheimer’s disease (AD). Our findings showed that, compared to the original MoCA, MCI sensitivity was substantially reduced when all auditory subtests were omitted, with the biggest contribution to the reduction coming from the delayed recall subtest. This Chapter highlights the contribution that hearing-dependent subtests have on the accuracy of the MoCA.

Manuscript II (Chapter 3) examines sex-related differences in the associations between MoCA scores and pure-tone average (PTA) in healthy older adults. MoCA-Modified scores were also calculated for all participants to assess the contribution of hearing-dependent items. Results showed that women with normal hearing were more likely to pass the MoCA compared to their counterparts with HL. In contrast, no associations were observed in men. Regression analysis showed an interaction between sex and PTA in the worse ear. PTAs were significantly correlated with both MoCA and MoCA-Modified scores in women, but not in men. This suggests significant sex-related differences in auditory-cognitive associations even when hearing-related test items are omitted.

Manuscript III (Chapter 4) examines sex-related differences in auditory-cognitive associations in a sample of individuals with MCI. In this cross-sectional analysis, we examined sex-related differences in hearing, as measured by both PTA and the Canadian Digit Triplet Test (CDTT), and cognition, as measured by the MoCA, Rey Auditory Verbal Learning (RAVLT), and the Brief Visuospatial memory test (BVMT-R). Women with better hearing on either measure outperformed their worse hearing counterparts on the MoCA. Women with normal hearing showed correlations between CDTT SRTs and MoCA and RAVLT scores. Men but not women showed an effect of hearing on the BVMT-R. Generally, this dissertation points to the existence of sex-related differences in auditory-cognitive associations and discusses potential mechanisms that underly these observations, including the common cause and information degradation hypotheses.

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