Aaliya Naaz
PhD, Dr. Sacher’s lab
I am investigating Tango2 protein localization and function in yeast and human myoblasts.
Our students
I am investigating Tango2 protein localization and function in yeast and human myoblasts.
I am currently working on an optogenetic tool to spatio-temporally control importin during anaphase and cytokinesis. The aim would be to further study the diverse functions of importin during mitosis using diverse methods.
My research focuses on using CRISPR and DNA repair mechanisms to streamline the design and construction of combinatorial pathways. I will apply this approach to different metabolic pathways to showcase the diversity and transferability we are currently able to achieve.
My research project focuses on the development and engineering of therapeutics tools based on RNA.
My current research focuses on understanding the molecular mechanism behind the lysosome membrane remodeling by Intralumenal Fragment (ILF) pathway in the model organism S. cerevisiae. I hope to shed light on the relationship of cell aging and related abnormal accumulation of lipids and proteins to lysosomal storage disorders, some types of cancers and neurodegenerative disorders.
I am engineering DNA oligonucleotides for the development of small molecule detection systems (biosensing).
My research focuses on hybridizing synthetic biology and microfluidics to create a novel, low-cost in-vitro diagnostic for infectious disease detection. I am working on building a protein-based biosensor for rapid analyte detection at the point-of-care.
I'm currently surveying the tumor suppressive genetic network that underlies chromosome 4p deletion, along with the genetic interaction network involving tumor suppressors within chr4p. With this, we hope to better understand the role of chr4p deletion in the initiation and progression of triple negative breast cancer.
I am working on computational design of therapeutics/drugs/peptides using machine learning and simulation methods, along with trying to better understand what's happening inside of deep learning models.
My research focuses on the detection and amplification of low-intensity light for molecular biology applications. I will be building a portable, low-cost fluorescent measurement system.
My research is centred on how microgravity impacts mammalian cells and stem cells. I am also working with digital microfluidics to improve stem cell workflows.
My research involves developing gene editing tools for constructing mutant cell lines harbouring large chromosomal deletions, in order to understand their role in triple negative breast cancer.
My research focuses on creating a yeast biomanufacturing platform for the production of organic acids. Organic acids are the building blocks of many complex polymers and chemicals used extensively in industry. This platform aims to decrease the reliance on petrol-derived organic acids, offering a more sustainable solution for the chemical building blocks we all rely on.
My research centers on developing sustainable methods towards natural product synthesis. Using directed evolution, molecular dynamics and high-throughput screening, I am developing efficient enzymatic pathways for glycosylated products. Furthermore, I am working on developing bioinformatics tools to predict efficiency of the designed artificial pathways.
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