Concordia University

http://www.concordia.ca/content/concordia/en/artsci/health-kinesiology-physiology/faculty.html

Faculty

Sylvia Santosa, PhD, RD (CDO)

Associate Professor, Health, Kinesiology and Applied Physiology
Canada Research Chair Tier II, Clinical Nutrition

Dr. Santosa conducts multidisciplinary research on the metabolic and cellular mechanisms of disease development and progression of obesity
Office: L-SP 165-21 
Richard J. Renaud Science Complex,
7141 Sherbrooke W.
Phone: (514) 848-2424 ext. 5841
Email: S.Santosa@concordia.ca
Availability: Dr. Santosa is currently recruiting MSc and PhD students and a postdoctoral fellow for her research program. Please contact her at s.santosa@concordia.ca if interested.

For more information on research and lab visit: www.monlab.ca

Education

Postdoctoral Fellowship, Mayo Clinic
PhD Nutritional Science, McGill University
RD, Member of the College of Dietitians of Ontario
BASc (Honours), Applied Human Nutrition, University of Guelph

Research

As a Canada Research Chair in Clinical Nutrition, Dr. Santosa conducts cutting edge research to identify the long-term effects of obesity, from the cell to the entire body.

Weight is a concern of millions of Canadians both on an individual and societal level. Despite existing public policy and individual weight interventions, we are still “growing” as a population with more Canadians overweight than not.

The metabolic and cellular mechanisms of why some overweight individuals develop diseases while others do not are not fully understood. Furthermore, in people with diseases, such as cardiovascular disease and diabetes, we do not fully understand how obesity affects the progression or treatment. Obesity treatment itself remains ineffective as most people who lose weight eventually gain it back. Dr. Santosa applies techniques in biology, physiology and nutrition to investigate and understand the underlying effects of obesity that contribute to weight gain and disease. 

Results from her studies will promote the development of better public health interventions from disease prevention to management. 

Dr. Santosa's research has been/is currently funded by the Heart and Stroke Foundation, the Canadian Foundation for Dietetic Research, the Quebec Bioimaging Network, the PERFORM Centre, NSERC, and a Canada Research Chair, Tier 2.

Current Projects

Currently recruiting graduate and postdoctoral trainees to join our research team.

Projects in the lab include:
-Examining regional differences in fat tissue in bariatric surgery patients
-Investigating differences in early vs late onset obesity
-Determining protein requirements in bariatric surgery patients
-Using imaging techniques to examine regional fat use and substrate oxidation

Trainees will learn cutting-edge techniques in human research, cellular and molecular biology, physiology, and nutrition. Techniques applied include flow cytometry, cell culture, PCR, body composition (DXA, CT, MRI), and nutritional analysis.   

Active Affiliations

Researcher, PERFORM Centre
Researcher, Sacre Coeur Hospital
Associate Researcher, CRIUGM

Editorial Board Member Activities

2019-present    International Journal of Obesity
2014-present    Scientific Reports

Professional Memberships

Canadian Nutrition Society
College of Dietitians of Ontario
The Obesity Society
Canadian Obesity Network
Société Québécoise de Lipidologie, de Nutrition, et de Metabolisme
Réseau de Recherche en Santé Cardiométabolique, Diabète, et Obésité
Diabète Québec


Teaching activities

EXCI 445

Nutrition in Sports and Exercise


Publications

Selected publications

Murphy J, Bacon S, Morais J, Tsoukas M, Santosa S§. Intra-abdominal adipose tissue quantification by alternative vs reference Methods: A systematic review and meta-analysis. Obesity: 2019:27;1115-22.

Kakinami L, Houle-Johnson S, Demissie Z, Santosa S, Fulton, JE. Meeting fruit and vegetable consumption and physical activity recommendations among adolescents intending to lose weight. Preventative Medicine Reports: 2018:13;11-15.

Delaney KZM, Vanstone CA, Weiler HA, Santosa S§. Regional adiposity and markers of inflammation in preschool aged children. Scientific Reports. 2018:2;15204 (7 pages).

Santosa S, Bush NC, Jensen MD. Acute testosterone deficiency alters adipose tissue fatty acid storage. Journal of Clinical Endocrinology and Metabolism. 2017:102;3056-64.

Murphy J, Moullec G, SantosaS§. Factors associated with adipocyte size reduction after weight loss interventions for overweight and obesity: a systemic review and meta-regression. Metabolism. 2017:67;31-40.

Santosa S, Bonnes S, Jensen MD. Acute female hypogonadism alters adipose tissue fatty acid storage factors and chylomicronemia. Journal of Clinical Endocrinology and Metabolism. 2016:101;2089-98.

Yang SQ, DeGuire JR, Agellon S, Lavery P, Mak I, Weiler HA, Santosa S§. Conjugated linoleic acid mitigates testosterone-related changes in body composition in male guinea pigs. Nutrition Research.2016:36;408-17.

Dam V, Sikdar T, Santosa S§. From Neutrophils to macrophages: Differences in regional adipose tissue depots. Obesity Reviews.2016:17;1-17.


Please see CV for complete list of publications.

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