Sylvia Santosa, PhD, RD (CDO)
Associate Professor, Exercise Science
Canada Research Chair Tier II, Clinical Nutrition
Richard J. Renaud Science Complex,
7141 Sherbrooke W.
|Phone:||(514) 848-2424 ext. 5841|
Dr. Santosa is currently recruiting MSc and PhD students and a postdoctoral fellow for her research program. Please contact her at firstname.lastname@example.org if interested.
Postdoctoral Fellowship, Mayo Clinic
PhD Nutritional Science, McGill University
RD, Member of the College of Dietitians of Ontario
BASc (Honours), Applied Human Nutrition, University of Guelph
As a Canada Research Chair in Clinical Nutrition, Dr. Santosa conducts cutting edge research to identify the long-term effects of obesity, from the cell to the entire body.
Weight is a concern of millions of Canadians both on an individual and societal level. Despite existing public policy and individual weight interventions, we are still “growing” as a population with more Canadians overweight than not.
The metabolic and cellular mechanisms of why some overweight individuals develop diseases while others do not are not fully understood. Furthermore, in people with diseases, such as cardiovascular disease and diabetes, we do not fully understand how obesity affects the progression or treatment. Obesity treatment itself remains ineffective as most people who lose weight eventually gain it back. Dr. Santosa applies techniques in biology, physiology and nutrition to investigate and understand the underlying effects of obesity that contribute to weight gain and disease.
Results from her studies will promote the development of better public health interventions from disease prevention to management.
Dr. Santosa's research is currently funded by the Heart and Stroke Foundation, NSERC, and a Canada Research Chair, Tier 2.
Currently recruiting graduate and postdoctoral trainees to join our research team.
Projects in the lab include:
-Examining regional differences in fat tissue in bariatric surgery patients
-Investigating differences in early vs late onset obesity
-Determining protein requirements in bariatric surgery patients
Trainees will learn cutting-edge techniques in human research, cellular and molecular biology, physiology, and nutrition. Techniques applied include flow cytometry, cell culture, PCR, body composition (DXA, CT, MRI), and nutritional analysis.
Researcher, Sacre Coeur Hospital
Associate Researcher, CRIUGM
Editorial Board Member, Scientific Reports
Canadian Nutrition Society
College of Dietitians of Ontario
The Obesity Society
Canadian Obesity Network
Société Québécoise de Lipidologie, de Nutrition, et de Metabolisme
Réseau de Recherche en Santé Cardiométabolique, Diabète, et Obésité
Nutrition in Sports and Exercise
Murphy J, Moullec G, Santosa S§. Factors associated with adipocyte size reduction after weight loss interventions foroverweight and obesity: a systemic review and meta-regression. Metabolism. 2017:67;31-40.
Dam V, Sikdar T, Santosa S§. FromNeutrophils to macrophages: Differences in regional adipose tissue depots. Obesity Reviews. 2016:17;1-17.
Santosa S, Bush NC, Jensen MD. Acute testosteronedeficiency alters adipose tissue fatty acid storage. Journal of Clinical Endocrinology and Metabolism. 2017:102;3056-64.
Varady KA*, DamV*, Horne M, Cruz R, Klempel MC, Kroeger CM, Santosa S§. Effects of weight loss via high fat vs lowfat alternate day fasting diets on free fatty acid profiles. Scientific Reports. 2015:5;7561 (6pages).
Santosa S, Swain J,Tchkonia T, Kirkland JL, Jensen MD. Inflammatory characteristics of adiposetissue collected by surgical excision vs. needle aspiration. International Journal of Obesity.2015:39;874-6.Please see CV for complete list of publications.