PhD Oral Exam - Neda Naghdi, Health, Kinesiology & Applied Physiology

When studying for a doctoral degree (PhD), candidates submit a thesis that provides a critical review of the current state of knowledge of the thesis subject as well as the student’s own contributions to the subject. The distinguishing criterion of doctoral graduate research is a significant and original contribution to knowledge.

Once accepted, the candidate presents the thesis orally. This oral exam is open to the public.

Abstract

The deep paraspinal muscles are essential for providing physical support and stability to the spinal column. They play a vital role in maintaining fine postural control of the spine and are responsible for controlling all movements of the vertebral column. These muscles work in coordination to ensure proper alignment and movement of the spine, thereby contributing to overall spinal health and function. Dysfunction or weakness in paraspinal muscles can lead to instability, poor posture, and increased risk of spinal injuries. Therefore, understanding the role of deep paraspinal muscles is crucial in maintaining spinal health and preventing musculoskeletal disorders. This summary highlights the significance of assessing both morphology and function of paraspinal muscles in common spinal disorders including chronic low back pain chronic (LBP) and degenerative cervical myelopathy (DCM). While previous studies have focused on either morphology or functional deficits separately, this dissertation aims to comprehensively investigate the structure-function relationship using advanced imaging techniques like magnetic resonance imaging (MRI) and ultrasound. Specifically, chapter three focuses on understanding the relationship between lumbar MF muscle morphology and function in chronic LBP patients, utilizing measures such as fatty infiltration, contraction, stiffness, and elasticity. Similarly, chapter four and five aim to assess cervical muscle morphology as predictors of prognosis and functional recovery in patients with DCM, both pre- and post-operatively. Such comprehensive evaluations are crucial for improving diagnosis, intervention, and therapeutic strategies in spinal disorders, ultimately enhancing patients’ clinical outcomes and quality of life. Finally, chapter six discusses the findings from chapters three, four and five and offers a general conclusion and recommendations for future research.