JOURNAL CLUB
The journal club’s objective is to assess recent journal articles and to discuss how the findings apply to current research.
Apply to present at an upcoming meeting
Graduate students and PostDocs are encouraged to apply to present papers.
To apply, please contact us at casb@concordia.ca
2019
- Intracellular delivery of mRNA to human primary T cells with microfuidic vortex shedding
Presented by Alaa Selim from the Shih Lab on September 25th, 2019 - Industrial brewing yeast engineered for the production of primary flavor determinants in hopped beer
Presented by Michael Pyne from the Martin Lab on September 11th, 2019 - Total synthesis of Escherichia coli with a recoded genome
Presented by Saima Rashid from the Whiteway Lab on August 28th, 2019 - Modular and tunable biological feedback control using a de novo protein switch
Presented by Mohamed Nasr from the Kwan and Martin Labs on July 31st, 2019 - RNA-guided DNA insertion with CRISPR-associated transposases
Presented by Mathieu Husser from the Piekny and Martin Labs on July 3rd, 2019 - Central dogma rates and the trade-off between precision and economy in gene expression
Presented by Giselle McCallum from the Potvin-Trottier Lab on June 19th, 2019 - Reprogramming the antigen specificity of B cells using genome-editing technologies
Presented by Courtney Gamache from the Kachroo Lab on June 5th, 2019 - Yeast-based synthetic biology platform for antimicrobial peptide production Presented by Jama Hagi-Yusuf from the Kwan Lab on May 22th, 2019
- Refactoring and Optimization of Light-Switchable Escherichia coli Two-Component Systems
Presented by Guy Soffer from the Shih Lab on May 8th, 2019 - Designer membraneless organelles enable codon reassignment of selected mRNAs in eukaryotes
Presented by Daniel Tsyplenkov from the Martin Lab on April 24th, 2019
- A Synthetic System That Senses Candida albicans and Inhibits Virulence Factors
Presented by Raha Omran from the Whiteway Lab on April 10th, 2019 - Complete biosynthesis of cannabinoids and their unnatural analogies in yeast Presented by Britanny Greco from the Kachroo Lab on March 27th, 2019
- Isolation of circulating tumor cells in non-small-cell-lung-cancer patients using a multi-flow microfluidic channel
Presented by Angela Quach from the Shih Lab on February 27th, 2019 - Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways
Presented by Bjorn Bean from the Martin Lab on February 20th, 2019. - Synthesis of 11-carbon terpenoids in yeast using protein and metabolic engineering
Presented by Anna Carolina Borges Pereira da Costa from the Whiteway Lab on January 30th, 2019 - Development of a multi-locus CRISPR gene drive system in budding yeast Presented by Sarmin Sultana from the Kachroo Lab on January 16th, 2019
- Synthetic switch to minimize CRISPR off-target effects by self-restricting Cas9 transcription and translation
Presented by Haoyu Wu from the Kwan Lab on December 5th, 2018 - Reprogramming human T cell function and specificity with non-viral genome targeting
Presented by Samuel Little from the Shih Lab on November 21st, 2018 - Iterative algorithm-guided design of massive strain libraries, applied to itaconic acid production in yeast
Presented by Mindy Melgar from the Martin Lab on November 7th, 2018 - Functional Genetic Variants Revealed by Massively Parallel Precise Genome Editing
Presented by Manjari Shrivastava from the Whiteway Lab on October 24th, 2018
- DNA-Linked Enzyme-Coupled Assay for Probing Glucosyltransferase Specificity
Presented by Maxim Soroko from the Kwan Lab on October 10th, 2018
- Quorum Sensing Can Be Repurposed To Promote Information Transfer between Bacteria in the Mammalian Gut
Presented by James Perry from the Shih Lab on September 26th, 2018 - Creating a functional single-chromosome yeast
Presented by Mudabir Abdullah from the Kachroo Lab on September 12th, 2018 - A semi-synthetic regulon enables rapid growth of yeast on xylose
Presented by James Bagley from the Martin Lab on August 29th, 2018. - Creating a functional single-chromosome yeast
Presented by Mudabir Abdullah from the Kachroo Lab on September 12th, 2018. - Metabolic engineering of a carbapenem antibiotic synthesis pathway in Escherichia coli
Presented by Lan Huong Nguyen from the Kwan Lab on August 1st, 2018. - Artificial Protein Scaffold System (AProSS): An efficient method to optimize exogenous metabolic pathways in Saccharomyces cerevisiae
Presented by Masoumeh Alizadeh from the Whiteway Lab on August 15th, 2018. - Prokaryotic nanocompartments form synthetic organelles in a eukaryote
Presented by Kaspar Kevvai from the Martin Lab on July 4th, 2018. - Synthesizing a Genetic Sensor Based on CRISPR-Cas9 for Specifically Killing p53-Deficient Cancer Cells
Presented by Raja Jain from the Shih Lab on July 25th, 2018. - Evolution of a split RNA polymerase as a versatile biosensor platform
Presented by Xiaohua Zhang from the Kwan Lab on June 6th, 2018. - Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES
Presented by Amjad Islam from the Whiteway Lab on June 20th, 2018. - Precise Editing at DNA Replication Forks Enables Multiplex Genome Engineering in Eukaryotes
Presented by Lauren Narcross from the Martin Lab on May 9th, 2018. - RNA-aptamers-in-droplets (RAPID) high-throughput screening for secretory phenotypes
Presented by Ehsan Moazami from the Shih Lab on May 23rd, 2018. - Rational Design of Mini-Cas9 for Transcriptional Activation
Presented by Jama Hagi-Yusuf from the Kwan Lab on April 11th, 2018. - Versatile and on-demand biologics co-production in yeast
Presented by Raha Parvizi Omran from the Whiteway Lab on April 25th, 2018. - DNA Origami Inside-Out Viruses
- Presented by Meghan Davies from the Martin Lab on March 14th, 2018.
- Hydrogel droplet single-cell processing: DNA purification, handling, release, and on-chip linearization
Presented by Fatemeh Ahmadi from the Shih Lab on March 28th, 2018. - Synchrony and pattern formation of coupled genetic oscillators on a chip of artificial cells
Presented by Laura Leclerc, from the Labs of Drs. Shih and Kwan, on February 14th, 2018. - Resetting the Yeast Epigenome with Human Nucleosomes
Presented by Manjari Shrivastava from the Whiteway Lab on February 28th, 2018. - Single-cell RT-PCR in microfluidic droplets with integrated chemical lysis
Presented by Amin Firouzeh from the Shih Lab on January 31st, 2018.
- A semi-synthetic organism that stores and retrieves increased genetic information
Presented by Alex Poisson from the Whiteway Lab on December 13th, 2017. - A stabilized microbial ecosystem of self-limiting bacteria using synthetic quorum-regulated lysis
Presented by Mohamed Nasr, from the Labs of Dr. Martin and Dr. Kwan, on December 7th, 2017. - Single-Cell Virology: On-Chip Investigation of Viral Infection Dynamics
Presented by Kenza Samlali from the Shih Lab on November 22nd, 2017. - Engineering glucose metabolism of Escherichia coli under nitrogen starvation
Presented by Lauren Narcross from the Martin Lab on November 1st, 2017. - Cell cycle entry triggers a switch between two modes of Cdc42 activation during yeast polarization
Presented by Anna Carolina Borges Pereira da Costa from the Whiteway Lab on October 18th, 2017. - Massively parallel single-amino-acid mutagenesis
Presented by Xiaohua Zhang from the Kwan Lab on October 4th, 2017. - Cell-free extract based optimization of biomolecular circuits with droplet microfluidics
Presented by Alaa Selim from the Shih Lab on September 20th, 2017. - A Straightforward Approach for 3D Bacterial Printing
Presented by Alex Vallerand from the Martin Lab on September 6th, 2017. - Systematic bacterialization of yeast genes identifies a near-universally swappable pathway
Presented by Pablo Godoy from the Whiteway Lab on August 30th, 2017. - Combinatorial metabolic engineering of Saccharomyces cerevisiae for terminal alkene production
Presented by Jama Hagi-Yusuf from the Kwan Lab on August 9th, 2017. - A modular yeast biosensor for low-cost point-of-care pathogen detection
Presented by William Cheney from the Martin Lab on July 12th, 2017. - Harnessing Type I and Type III CRISPR-Cas systems for genome editing
Presented by Michael Pyne from the Martin Lab on June 28th, 2017. - Engineering RGB color vision into Escherichia coli
Presented by Mathieu Husser from the Shih Lab on June 14th, 2017. - Intelligent Microbial Heat-Regulating Engine (IMHeRE) for Improved Thermo-Robustness and Efficiency of Bioconversion
Presented by Meghan Davies from the Martin Lab on May 17th, 2017. - Design of a synthetic yeast genome
Presented by Jaideep Mallick from the Whiteway Lab on May 3rd, 2017. - Multigene Pathway Engineering with Regulatory Linkers (M-PERL)
Presented by James Perry from the Shih Lab on April 19th, 2017. - A glucose-sensing toggle switch for autonomous, high productivity genetic control
Presented by Leanne Bourgeois from the Martin Lab on April 5th, 2017. - Multiparameter Optimization in Directed Evolution: Engineering Thermostability, Enantioselectivity, and Activity of an Epoxide Hydrolase
Presented by Ifthiha Mohideen from the Kwan Lab on March 22nd, 2017. - An ambiguity principle for assigning protein structural domains
Presented by Laura Leclerc, from the Labs of Drs. Shih and Kwan, on March 8th, 2017. - Synthesis and cell-free cloning of DNA libraries using programmable microfluidics
Presented by Ehsan Moazami from the Shih Lab on February 22nd, 2017. - Ultrahigh-throughput–directed enzyme evolution by absorbance-activated droplet sorting (AADS)
Presented by Fatemeh Ahmadi from the Shih Lab on February 8th, 2017. - Rapid generation of CRISPR/dCas9-regulated, orthogonally repressible hybrid T7-lac promoters for modular, tuneable control of metabolic pathway fluxes in Escherichia coli
Presented by Lauren Narcross from the Martin Lab on January 11th, 2017. - A Tunable Protein Piston That Breaks Membranes to Release Encapsulated Cargo
Presented by Alex Campbell, Martin Lab alumnus, on January 25th, 2017.
- Portable, On-Demand Biomolecular Manufacturing
Presented by Mohamed Nasr, from the Labs of Dr. Martin and Dr. Kwan, on November 30th, 2016. - Artificial Symmetry-Breaking for Morphogenetic Engineering Bacterial Colonies
Presented by Mindy Melgar from the Martin Lab on December 14th, 2016 - Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells
Presented by Hugo Sinha from the Shih Lab on November 16th, 2018. - Metabolic engineering of Escherichia coli using synthetic small regulatory RNAs
Presented by Jama Hagi-Yusuf from the Kwan Lab on November 2nd, 2016. - Programming cells by multiplex genome engineering and accelerated evolution
Presented by Michael Pyne from the Martin Lab on October 19th, 2016. - Programmable large area digital microfluidic array with integrated droplet sensing for bioassays
Presented by Amin Firouzeh from the Shih Lab on October 5th, 2016. - Spatiotemporal microbial evolution on antibiotic landscapes
Presented by Alex Vallerand from the Martin Lab on September 21st, 2016. - Design, synthesis, and testing toward a 57-codon genome
Presented by Gustavo Leite from the Martin Lab on September 7th, 2016.