Temperature plays an essential role in biological systems, affecting a variety of their properties. For example, the rate of cell division and consequently tissue growth. Thus, given the importance of temperature in cellular events the ability to measure the temperature at intracellular and intercellular levels are of paramount importance especially for cancer cells. This could have valuable repercussions leading to novel insight about its pathology and physiology, which could lead to innovative understanding into cancer treatment and diagnoses. Presently, the temperature monitoring of tissues is mainly carried out using ultrasound thermometry, microwave and magnetic resonance thermometry. However, these techniques suffer from low spatial and temporal resolution, justifying the urge for the development of other types of non-contact temperature sensors. The use of luminescent Lanthanide-doped upconverting nanoparticles (Ln-UCNPs) are promising in this respect, due to the high spatial resolution of the fluorescence technique, the possibility of NIR excitation/imaging of these nanoparticles which leads to low photodamage to the tissue and their high penetration depth. This postdoctoral project will explore the use of bilayer-coated Ln-UCNPs for thermal mapping of intracellular temperatures as well as thermal therapy and will include experimental and computational chemistry approaches.
Academic qualifications required
PhD in Chemistry or Materials Science or related fields with experience in nano(bio)science, spectroscopy and computational methodologies.
Applicants must not currently hold a postdoctoral appointment at Concordia
Priority will be given to postdoctoral fellows who have obtained their PhD from another university although in exceptional cases Concordia graduates may be considered
Please include the reference number with your application
One to three (1-3) page research statement demonstrating fit with the program described above.
Current curriculum vitae demonstrating research excellence and a capacity for leadership in the domain (maximum 5 pages).
Two letters of reference from academic supervisors or current employers to be sent via e-mail directly to Niyusha Samadi.
The prestigious two-year Horizon Postdoctoral Fellowships are valued at $50,000 per year plus benefits and full access to Concordia’s services, including GradProSkills.
Concordia University is a vibrant research and teaching environment, with state-of-the-art research facilities and many research centers. Concordia is located in Montreal, Canada, a diverse and creative city, often ranked as offering one of the best quality of living experiences in North America.
Concordia University is committed to Employment Equity and encourages applications from women, Aboriginal Peoples, visible minorities, ethnic minorities, and persons with disabilities.