Principal Investigator: Dr. Richard Courtemanche
While there have been great strides in inspecting rules and equipment designed to assess and treat concussions there remains a knowledge gap concerning the assessment and treatment of the post-concussion signs and symptoms. What is needed is the formalization of a set of physiological variables that could predict the capacity of the athlete to return to play following a concussion. By using novel EEG techniques, this study will biomechanically evaluate the recovery of function in terms of reaction time, response selection, and balance control.
Principle Investigator: Dr. Sylvia Santosa
The metabolic and cellular mechanisms of why some overweight individuals develop diseases while others do not are not fully understood. Furthermore, there is a lack of effective ways to treat obesity, as most people who lose weight eventually regain it. The goal of this novel research program is to identify the long-term effects of obesity, from the cell to the entire body, that contribute to disease development and weight regain. This multi-disciplinary research program combines cell biology, nutrition and fat metabolism with analysis taking place in the Nutrition, Obesity and Metabolism Laboratory (NOM lab) located at PERFORM.
Principle Investigator: Dr. Karen Li
Research shows that as we get older increasing levels of cognitive capacity are required for basic motor tasks such walking or balancing. It has also been demonstrated that age-related hearing loss demands more cognitive capacity for active listening. This study will combine these two areas of research to advance existing knowledge about underlying causes of age related losses of hearing and mobility. PERFORM's facilities will enable participants to undergo analytical balance assessment and cognitive tests while doing exercise on the latest instrumentation available in these fields of study.
Principle Investigator: Dr. Peter Darlington
The object of this research program is to explore exercise as a natural immune system suppressor for slowing the progression of autoimmune diseases such as multiple sclerosis. The details of how exercise changes the immune system, and what hormones are responsible for exerting such change are not known. This pilot study is designed to establish the means to measure immune-cell function in humans undergoing a moderate exercise routine. The results will help launch a larger study on healthy subjects and a similar project with multiple sclerosis patients in collaboration with colleagues from the Montreal Neurological Institute and McGill University.
Principle Investigator: Dr. Véronique Pépin
Several exercise training approaches have been used in pulmonary rehabilitation, each demonstrating some merit, however these need to be compared to one another to better guide healthcare practitioners who design exercise programs for chronic obstructive pulmonary disease (COPD) patients. Using PERFORM's conditioning and rehabilitation floor and cardiopulmonary suite, this study will compare three different exercise training approaches commonly used in pulmonary rehabilitation to determine which one is optimal in COPD patients.
Applying for Research
Researchers interested in advancing their work at the PERFORM Center must follow these steps:
- Contact the Research Coordinator to discuss initial concept;
- Submit an application form to PERFORM's Scientific Review Committee (SRC);
- Upon favorable mention from the SRC, researchers meet with PERFORM's Cross-Functional Evaluation Team to discuss implementation;
- When studies involve human subjects, ethics approval is required from the appropriate board per the scope of the study.