Zachary Schiffman - Concordia University

VALIDATION SCIENTIST

Montreal, QC, Canada

Conducted a validation study on the Protein Design application within Molecular Operating Environment (MOE) software
Co-authored a research paper on MOE’s ability to accurately predict the influence of singlepoint mutations on protein thermostability
Validated the protein thermostability scoring function implemented in MOE and evaluated its potential for improvement
Collaborated with research and development team on ways to improve predictability of protein thermostabiliy
Participated in CCG’s annual UGM conference emphasizing advantages of using MOE for in silico protein modeling to customers
Developed and optimized a novel method for mapping epitopes and/or protein-protein binding sites using MOE software
Co-authored a research paper on the identification and characterization of epitopes and/or protein-protein binding sites using the protein-protein interaction fingerprints (PPIF) application in MOE
Refined optimal clustering parameters implemented by MOE for mapping epitopes and/or protein-protein binding sites in silico
Engaged with customers at CCG’s annual UGM conference highlighting MOE’s potential in predicting epitopes using protein-protein interaction fingerprints

RESEARCH ASSOCIATE

Laval, QC, Canada

Designed and implemented novel experiments critical to advancement and acceleration of KTI pipeline
Established a mode of action (MOA) outlining proprietary KTI technology and biological processes stimulated through Fluorescence Biomodulation (FB)
Communicated on a regular basis with research and development and corporate teams as well as inventors to identify aspects of the proprietary KTI technology which required additional experimental evidence
Evaluated in vitro gene expression using qPCR and in vitro protein expression using ELISA and Western Blotting

Institute for Co-operative Education