James G. Pfaus, PhD, IF
Concordia University Research Fellow
Cross-appointment (Graduate Program), Biology
Cross-appointment (Graduate Program), Chemistry and Biochemistry
Cross-appointment (Graduate Program), Exercise Science
Sexual behavior, animal, human, neuropharmacology, neuroendocrinology
Overview: My research is generally concerned with the neurochemical and molecular events that subserve sexual behavior and neuroendocrine functions. I am interested in the role of brain monoamine and neuropeptide systems in sexual arousal, desire, reward, and inhibition in laboratory animals. I am also interested in the inhibitory and disinhibitory effects of drugs of abuse on sexual behavior. Current research examines the role played by steroid hormones, neurotransmitter systems, and cell signalling mechanisms, in the neuronal and behavioral responses to primary and conditioned sexual stimuli, especially those that induce sexual partner preferences. The neurochemical and molecular systems activated by primary and conditioned sexual stimuli are being explored using a combination of in vivo techniques such as microdialysis, and ex vivo techniques such as immunocytochemistry, in situ hybridization histochemistry, and autoradiography.
My research in human sexual function focuses on subjective and objective measures of sexual desire and pleasure in women and men, and how such measures are altered by different types of erotic stimulation. We are also exploring the sexual functioning of individuals under stress or with anxiety disorders.
My research is funded by the Canadian Institutes of Health Research (CIHR) and the Natural Sciences and Engineering Research Council of Canada (NSERC). I have also held consulting grants from several pharmaceutical and biotech companies, for example, Boehringer Ingelheim, Eli Lilly, Pfizer, Lundbeck, Palatin, and Emotional Brain, to examine potential sexual side-effects of different psychiatric medications and for work on the identification of new pharmacological tools to treat male and female sexual dysfunctions.
Current lab members
Lucia Farisello (Psychology - Cognitive)
Katuschia Germé (Biology - Behavioral Neuroscience)
M. Dean Graham (Psychology - Behavioral Neuroscience)
Christine Gerson (Psychology - Behavioral Neuroscience)
Conall Mac Cionnaith (Psychology - Behavioral Neuroscience)
Maria Santaguida (Psychology - Cognitive)
Gonzalo Quintana Zunino (Psychology - Behavioral Neuroscience)
Julie Shilhan (Psychology - Clinical)
Lindsay Sparks (Psychology - Behavioral Neuroscience)
Karine Elalouf (MA - Cognitive)
Publication and Video linksLa Presse - SCIENCE - Sexe, rats et rock'n'roll
BTMTL: Concordia Professor Jim Pfaus on Aphrodisiacs
CTV News Montreal - The secret to love
Pfaus, J.G. PersistentGenital Arousal Disorder: Fact or fiction? (Commentary). J. Sex Med. [In press]
Hussain D, Graham MD, Pfaus JG, Woodside BL, Brake WG (2017) Reproductive experience decreases dopamine D2 receptor binding in the dorsal striatum of the female rat. J Neuroendocrinol. [In press]
Jones, S.L., Ismail, N., Pfaus, J.G.(2017). Facilitation of sexual behavior in ovariectomized rats by estradiol and testosterone: A preclinical model of androgen effects on female sexual desire. Psychoneuroendocrinology [In press]
Pfaus, J.G., Scardochio,T., Parada, M., Gerson, C., Quintana, G.R., Coria-Avila, G.A. (2016). Do ratshave orgasms? Socioaffective Neuroscience and Psychology, 6, 31883.
Goldstein, I., Kim, N.N., Clayton, A.H., DeRogatis, L.R., Giraldi, A.,Parish, S.J., Pfaus, J.G., Simon,J.A., Kingsberg, S.A., Meston, C., Stahl, S.M., Wallen, K., & Worsley, R. (2016). Understanding the management of hypoactive sexual desire disorder. Mayo Clinic Proceedings, [In press]Juster, R. P., Almeida, D., Cardoso, C., Raymond, C., Johnson, P. J., Pfaus, J.G., Mendrek, A., Duchense, A., Pruessner, J.C., & Lupien, S.J. (2016). Gonads and strife: Sex hormones vary according to sexual orientation for women and stress indices for both sexes. Psychoneuroendocrinology, 72, 119-130. Parish SJ, Goldstein AT, Goldstein SW, Goldstein I, Pfaus JG, Clayton AH, Giraldi A, Simon J, Althof SE, Bachmann G, Komisaruk B, Levin R, Kellogg Spadt S, Kingsberg SA, Perelman MA, Waldinger M, Whipple B (2016) Toward a more evidence-based nosology and nomenclature for female sexual dysfunctions – Part II. J Sex Med., 13, 1888-1906.
Persson TJ, Ryder AG, Pfaus JG (2016) Comparing subjective ratings of sexual arousal and desire in partnered sexual activities from women of different sexual orientations. Arch Sex Behav., 45, 1391-1402.
Graham MD, Gardner Gregory J, Hussain D, Brake WG, Pfaus JG (2015) Ovarian steroids alter dopamine receptor populations in the medial preoptic area of female rats: implications for sexual motivation, desire, and behaviour. Eur J Neurosci 42:3138-3148. [PubMed] [Content]
Holley A, Bellevue S, Vosberg D, Wenzel K, Roorda S Jr, Pfaus JG (2015) The role of oxytocin and vasopressin in conditioned mate guarding behavior in the female rat. Physiol Behav 144:7-14. [PubMed] [Content]
Jones SL, Antonie RA, Pfaus JG (2015) The inhibitory effects of corncob bedding on sexual behavior in the ovariectomized Long-Evans rat treated with estradiol benzoate are overcome by male cues. Horm Behav 72:39-48. [PubMed] [Content]
Jones SL, Cordeaux E, Germé K, Pfaus JG (2015) Behavioral defeminization by prenatal androgen treatment in rats can be overcome by sexual experience in adulthood. Horm Behav 73:104-115. [PubMed] [Content]
Jones SL, Gardner Gregory J, Pfaus JG (2015) RU486 facilitates or disrupts the sensitization of sexual behaviors by estradiol in the ovariectomized Long-Evans rat: Effect of timecourse. Horm Behav 75:1-10. [PubMed] [Content]
Jones SL, Farisello L, Mayer-Heft N, Pfaus JG (2015) Repeated administration of estradiol promotes mechanisms of sexual excitation and inhibition: Glutamate signaling in the ventromedial hypothalamus attenuates excitation. Behav Brain Res 291:118-129. [PubMed] [Content]
Jones SL, Germé K, Graham MD, Roy P, Gardner Gregory J, Rosenbaum S, Parada M, Pfaus JG (2015) Vaginocervical stimulation attenuates the sensitization of appetitive sexual behaviors by estradiol benzoate in the ovariectomized rat. Horm Behav 75:70-77. [PubMed] [Content]
Juster RP, Hatzenbuehler ML, Mendrek A, Pfaus JG, Smith NG, Johnson PJ, Lefebvre-Louis JP, Raymond C, Marin MF, Sindi S, Lupien SJ, Pruessner JC (2015) Sexual orientation modulates endocrine stress reactivity. Biol Psychiatry 77:668-676. [PubMed] [Content]
Kingsberg SA, Clayton AH, Pfaus JG (2015) The female sexual response: current models, neurobiological underpinnings and agents currently approved or under investigation for the treatment of hypoactive sexual desire disorder. CNS Drugs 29:915-933. [PubMed] [Content]
Persson TJ, Pfaus JG (2015) Bisexuality and mental health: future research directions. J Bisex 15:82-98. [Content]
Persson TJ, Pfaus JG, Ryder AG (2015) Explaining mental health disparities for non-monosexual women: abuse history and risky sex, or the burdens of non-disclosure? Soc Sci Med 128:366-73. [PubMed] [Content]
Triana-Del Rio R, Tecamachaltzi-Silvarán MB, Díaz-Estrada VX, Herrera-Covarrubias D, Corona-Morales AA, Pfaus JG, Coria-Avila GA (2015) Conditioned same-sex partner preference in male rats is facilitated by oxytocin and dopamine: effect on sexually dimorphic brain nuclei. Behav Brain Res 283:69-77. [PubMed] [Content]
Jones SL, Pfaus JG (2014) Sensitization of sexual behaviors in ovariectomized Long-Evans rats is induced by a subthreshold dose of estradiol benzoate and attenuated by repeated copulation. Horm Behav 66: 655-662. [PubMed]
Persson TJ, Pfaus JG, Ryder AG (2014) Explaining mental health disparities for non-monosexual women: Abuse history and risky sex, or the burdens of non-disclosure? Soc Sci Med. [PubMed] [Content]
Farmer MA, Leja A, Foxen-Craft E, Chan L, MacIntyre LC, Niaki T, Chen M, Mapplebeck JC, Tabry V, Topham L, Sukosd M, Binik YM, Pfaus JG, Mogil JS (2014) Pain reduces sexual motivation in female but not male mice. J Neurosci 34:5747-5753. [PubMed] [Content]
Cibrian-Llanderal T, Triana-Del Rio R, Tecamachaltzi-Silvaran M, Pfaus JG, Manzo J, Garcia LI, Coria-Avila GA (2014) Cohabitation between male rats after ejaculation: effects on conditioned partner preference. Physiol Behav 128:303-308. [PubMed] [Content]
Georgescu M, Afonso VM, Graham MD, Pfaus JG (2014) Glutamate release in the ventromedial hypothalamus of the female rat during copulation: modulation by estradiol. Horm Behav 65:119-126. [PubMed] [Content]
Pfaus JG, Erickson KA, Talianakis S (2013) Somatosensory conditioning of sexual arousal and copulatory behavior in the male rat: a model of fetish development. Physiol Behav 122:1-7. [PubMed] [Content]
Bitzer J, Giraldi A, Pfaus J (2013) Sexual desire and hypoactive sexual desire disorder in women. Introduction and overview. Standard operating procedure (SOP Part 1). J Sex Med 10:36-49. [PubMed] [Content]
Bitzer J, Giraldi A, Pfaus J (2013) A standardized diagnostic interview for hypoactive sexual desire disorder in women: standard operating procedure (SOP Part 2). J Sex Med 10:50-57. [PubMed] [Content]
Pfaus JG, Scepkowski LA, Marson L, Georgiadis JR (2013) Biology of the sexual response. In Tolman, DL & Diamond, LM (Eds.), APA Handbook of Sexuality and Psychology, pp 143-203, Washington DC: APA Press.
Kim SW, Schenck CH, Grant JE, Yoon G, Dosa PI, Odlaug BL, Schreiber LRN, Hurwitz TD, Pfaus JG (2013) Neurobiology of sexual desire. NeuroQuantology 11:332-359. [Content]
Jones SL, Ismail N, King L, Pfaus JG (2012) The effects of chronic administration of testosterone propionate with or without estradiol on the sexual behavior and plasma steroid levels of aged female rats. Endocrinology 153:5928-5939. [PubMed] [Content]
Graham MD, Pfaus JG (2012) Differential effects of dopamine antagonists infused to the medial preoptic area on the sexual behavior of female rats primed with estrogen and progesterone. Pharmacol Biochem Behav 102:532-539. [PubMed] [Content]
Paredes-Ramos P, Miquel M, Manzo J, Pfaus JG, Lopez-Meraz ML, Coria-Avila GA (2012) Tickling in juvenile but not adult female rats conditions sexual partner preference. Physiol Behav 107:17-25. [PubMed] [Content]
Georgescu M, Cyr D, Pfaus JG (2012) AMPA/kainate receptors in the ventromedial hypothalamus mediate the effects of glutamate on estrus termination in the rat. Pharmacol Biochem Behav 102:146-150. [PubMed] [Content]
Pfaus JG, Kippin TE, Coria-Avila GA, Gelez H, Afonso VM, Ismail N, Parada M (2012) Who, what, where, when (and maybe even why)? How the experience of sexual reward connects sexual desire, preference, and performance. Arch Sex Behav 41:31-62. [PubMed] [Content]
Cacioppo S, Bianchi-Demicheli F, Frum C, Pfaus JG, Lewis JW (2012) The common neural bases between sexual desire and love: a multilevel kernel density fMRI analysis. J Sex Med 9:1048-1054. [PubMed] [Content]
Giraldi A, Rellini A, Pfaus JG, Bitzer J, Laan E, Jannini EA, Fugl-Meyer AR (2011) Questionnaires for assessment of female sexual dysfunction: A review and proposal for a standardized screener. J Sex Med 8:2681-2706. [PubMed] [Content]
Parada M, Abdul-Ahad F, Censi S, Sparks L, Pfaus JG (2011) Context alters the ability of clitoral stimulation to induce a sexually-conditioned partner preference in the rat. Horm Behav 59:520-527. [PubMed] [Content]
Paredes-Ramos P, Jones SL, Pérez-Pouchoulén M, Coria-Avila GA, Pfaus JG (2011) Progressive abdominal enlargement and limb weakness in aged, hormonally treated female rats. Lab Anim (NY) 40:14-17. [PubMed] [Content]
Coria-Avila GA, Pfaus JG, Cibrian-Llanderal T, Tecamachaltzi-Silvaran M, Triana-Del Rio R, Montero-Domínguez F, Paredes-Ramos P, López-Meraz L, Manzo J, García L (2010) Cómo aprender a comportarse… sexualmente. E Neurobiolgia Revista (in press).
Montorsi F, Adaikan G, Becher E, Giuliano F, Khoury S, Lue TF, Sharlip I, Althof SE, Andersson KE, Brock G, Broderick G, Burnett A, Buvat J, Dean J, Donatucci C, Eardley I, Fugl-Meyer KS, Goldstein I, Hackett G, Hatzichristou D, Hellstrom W, Incrocci L, Jackson G, Kadioglu A, Levine L, Lewis RW, Maggi M, McCabe M, McMahon CG, Montague D, Montorsi P, Mulhall J, Pfaus J, Porst H, Ralph D, Rosen R, Rowland D, Sadeghi-Nejad H, Shabsigh R, Stief C, Vardi Y, Wallen K, Wasserman M (2010) Summary of the recommendations on sexual dysfunctions in men. J Sex Med 7:3572-3588. [PubMed] [Content]
Pfaus JG, Wilkins MF, Dipietro N, Benibgui M, Toledano R, Rowe A, Couch MC (2010) Inhibitory and disinhibitory effects of psychomotor stimulants and depressants on the sexual behavior of male and female rats. Horm Behav 58:163-176. [PubMed] [Content]
Ismail N, Laroche C, Girard-Beriault F, Menard S, Greggain-Mohr JA, Pfaus JG (2010) Conditioned ejaculatory preference in male rats paired with haloperidol-treated females. Physiol Behav 100:116-121. [PubMed] [Content]
Cibrian-Llanderal T, Tecamachaltzi-Silvaran M, Triana-Del Rio R, Pfaus JG, Manzo J, Coria-Avila GA (2010) Clitoral stimulation modulates appetitive sexual behavior and facilitates reproduction in rats. Physiol Behav 100:148-153. [PubMed] [Content]
Pfaus JG, Tse TL, Werk CM, Chanda ML, Leblonde A, Harbour VL, Chapman CA (2009) Enhanced synaptic responses in the piriform cortex associated with sexual stimulation in the male rat. Neuroscience 164:1422-1430. [PubMed] [Content]
Ismail N, Girard-Bériault F, Nakanishi S, Pfaus JG (2009) Naloxone, but not flupenthixol, disrupts the development of conditioned ejaculatory preference in the male rat. Behav Neurosci 123:992-999. [PubMed] [Content]
Georgescu M, Sabongui C, Del Corpo A, Marsan L, Pfaus JG (2009). Vaginocervical stimulation induces Fos in glutamate neurons in the ventromedial hypothalamus: attenuation by estrogen and progesterone. Horm Behav 56:450-456. [PubMed] [Content]
Korda JB, Pfaus JG, Kellner CH, Goldstein I (2009) Persistent genital arousal disorder (PGAD): case report of long-term symptomatic management with electroconvulsive therapy. J Sex Med 6:2901-2909. [PubMed] [Content]
Korda JB, Pfaus JG, Goldstein I (2009) Persistent genital arousal disorder: a case report in a woman with lifelong PGAD where serendipitous administration of varenicline tartrate resulted in symptomatic improvement. J Sex Med 6:1479-1486. [PubMed] [Content]
Ismail N, Gelez H, Lachapelle I, Pfaus JG (2009) Pacing conditions contribute to the conditioned ejaculatory preference for a familiar female in the male rat. Physiol Behav 96:201-208. [PubMed] [Content]
Burgdorf J, Kroes RA, Moskal JR, Pfaus JG, Brudzynski SM, Panksepp J (2008) Ultrasonic vocalizations of rats (Rattus norvegicus) during mating, play, and aggression: Behavioral concomitants, relationship to reward, and self-administration of playback.J Comp Psychol 122:357-367. [PubMed] [Content]
Coria-Avila GA, Hernández-Aguilar ME, Toledo-Cárdenas R, García-Hernández LI, Manzo J, Pacheco P, Miquel M, Pfaus JG (2008) Bases biológicas y neurales de las preferencias de pareja en roedores: modelos para entender los vínculos afectivos en humanos. [Biological and neural bases of partner preferences in rodents: models to understand human pair bonds]. Rev Neurol 47:209-214. [PubMed] [Content]
Coria-Avila GA, Solomon CE, Vargas EB, Lemme I, Ryan R, Ménard S, Gavrila AM, Pfaus JG (2008)Neurochemical basis of conditioned partner preference in the female rat: I. Disruption by naloxone.Behav Neurosci 122:385-395. [PubMed] [Content]
Coria-Avila GA, Gavrila AM, Boulard B, Charron N, Stanley G, Pfaus JG (2008) Neurochemical basis of conditioned partner preference in the female rat: II. Disruption by flupenthixol.Behav Neurosci 122:396-406. [PubMed] [Content]
Coria-Avila GA, Pfaus JG, Miquel M, Pacheco P, Manzo J (2008) Preferencias condicionadas por sexo y drogas: comparación de las bases neurales. [Conditioned preferences induced by sex and drugs: a comparison of the neural bases]. Rev Neurol 46:213-218. [PubMed] [Content]
Leri F, Sorge RE, Cummins E, Woehrling D, Pfaus JG, Stewart J (2007) High-dose methadone maintenance in rats: effects on cocaine self-administration and behavioral side effects.Neuropsychopharmacology 32:2290-2300. [PubMed] [Content]
Rossler AS, Pfaus JG, Kia HK, Bernabe J, Alexandre L, Giuliano F (2006) The melanocortin agonist, melanotan II, enhances proceptive sexual behaviors in the female rat. Pharmacol Biochem Behav 85:514-521. [PubMed] [Content]
Pfaus JG (2006) Of rats and women: preclinical insights into the nature of female sexual desire. Sexual and Relationship Therapy 21:463-476. [Content]
Pfaus JG, Manitt C, Coopersmith CB (2006) Effects of pelvic, pudendal, or hypogastric nerve cuts on Fos induction in the rat brain following vaginocervical stimulation. Physiol Behav 89:627-636. [PubMed] [Content]
Coria-Avila GA, Menard S, Boulard B, Ryan R, Lemme I, Pfaus JG (2006) Fecal bulking in a frequently mated female rat. Colonic obstruction due to severe vaginal distension. Lab Anim (NY) 35:20-23. [PubMed] [Content]
Georgescu M, Pfaus JG (2006) Role of glutamate receptors in the ventromedial hypothalamus in the regulation of female rat sexual behaviors I. Behavioral effects of glutamate and its selective receptor agonists AMPA, NMDA and kainate. Pharmacol Biochem Behav 83:322-332. [PubMed] [Content]
Georgescu M, Pfaus JG (2006) Role of glutamate receptors in the ventromedial hypothalamus in the regulation of female rat sexual behaviors. II. Behavioral effects of selective glutamate receptor antagonists AP-5, CNQX, and DNQX. Pharmacol Biochem Behav 83:333-341. [PubMed] [Content]
Pfaus JG, Scepkowski LA (2005)The biologic basis for libido. Curr Sex Health Rep 2:95-100. [Content]
Vasey PL, Pfaus JG (2005) A sexually dimorphic hypothalamic nucleus in a macaque species with frequent female-female mounting and same-sex sexual partner preference. Behav Brain Res 157:265-272. [PubMed] [Content]
Pfaus JG, Shadiack A, Van Soest T, Tse M, Molinoff P (2004) Selective facilitation of sexual solicitation in the female rat by a melanocortin receptor agonist. Proc Natl Acad Sci U S A 101:10201-10204. [PubMed] [Content]
Pfaus JG (2004) State of the art II: neurophysiology of sexual desire: L2: neurophysiology of sexual desire.J Sex Med 1:2-3. [Content]
Kippin TE, Sotiropoulos V, Badih J, Pfaus JG (2004) Opposing roles of the nucleus accumbens and anterior lateral hypothalamic area in the control of sexual behaviour in the male rat. Eur J Neurosci 19:698-704. [PubMed] [Content]
Kippin TE, Samaha AN, Sotiropoulos V, Pfaus JG (2001) The development of olfactory conditioned ejaculatory preferences in the male rat. II. Parametric manipulation of conditioning session number and duration. Physiol Behav 73:471-485. [PubMed] [Content]
Pfaus JG (2000) Understanding sex in the brain. Cell 101:153-156. [Content]
Pfaus JG, Smith WJ, Coopersmith CB (1999) Appetitive and consummatory sexual behaviors of female rats in bilevel chambers. I. A correlational and factor analysis and the effects of ovarian hormones. Horm Behav 35:224-240. [PubMed] [Content]
Pfaus JG, Smith WJ, Byrne N, Stephens G (2000) Appetitive and consummatory sexual behaviors of female rats in bilevel chambers. II. Patterns of estrus termination following vaginocervical stimulation. Horm Behav 37:96-107. [PubMed] [Content]
Pfaus JG, Smith WJ, Coopersmith CB (1999) Appetitive and consummatory sexual behaviors of female rats in bilevel chambers. I. A correlational and factor analysis and the effects of ovarian hormones. Horm Behav 35:224-240. [PubMed] [Content]
Kippin TE, Talianakis S, Schattmann L, Bartholomew S, Pfaus JG (1998) Olfactory conditioning of sexual behavior in the male rat (Rattus norvegicus). J Comp Psychol 112:389-399. [Content]
Pfaus JG, Marcangione C, Smith WJ, Manitt C, Abillamaa H (1996) Differential induction of Fos in the female rat brain following different amounts of vaginocervical stimulation: modulation by steroid hormones. Brain Res 741:314-330. [PubMed] [Content]
Edelstein K, Pfaus JG, Rusak B, Amir S (1995) Neonatal monosodium glutamate treatment prevents effects of constant light on circadian temperature rhythms of adult rats. Brain Res 675:135-142. [PubMed] [Content]
Pfaus JG, Jakob A, Kleopoulos SP, Gibbs RB, Pfaff DW (1994) Sexual stimulation induces Fos immunoreactivity within GnRH neurons of the female rat preoptic area: interaction with steroid hormones. Neuroendocrinology 60:283-290. [PubMed] [Content]
Pfaus JG, Kleopoulos SP, Mobbs CV, Gibbs RB, Pfaff DW (1993) Sexual stimulation activates c-fos within estrogen-concentrating regions of the female rat forebrain. Brain Res 624:253-267. [PubMed] [Content]
McCarthy MM, Brooks PJ, Pfaus JG, Brown HE, Flanagan LM, Schwartz-Giblin S, Pfaff DW (1993) Antisense oligodeoxynucleotides in behavioral neuroscience. Neuroprotocols 2:67-74. [Content]
Wenkstern D, Pfaus JG, Fibiger HC (1993) Dopamine transmission increases in the nucleus accumbens of male rats during their first exposure to sexually receptive female rats. Brain Res 618:41-46. [PubMed] [Content]
Pfaus JG, Pfaff DW (1992) Mu-, delta-, and kappa-opioid receptor agonists selectively modulate sexual behaviors in the female rat: differential dependence on progesterone. Horm Behav 26:457-473. [PubMed] [Content]
Damsma G, Pfaus JG, Wenkstern D, Phillips AG, Fibiger HC (1992) Sexual behavior increases dopamine transmission in the nucleus accumbens and striatum of male rats: comparison with novelty and locomotion. Behav Neurosci 106:181-191. [PubMed] [Content]
Fibiger HC, Nomikos GG, Pfaus JG, Damsma G (1992) Sexual behavior, eating and mesolimbic dopamine. Clin Neuropharmacol 15 Suppl 1 Pt A:566A-567A. [PubMed]
Kaplitt MG, Pfaus JG, Kleopoulos SP, Hanlon BA, Rabkin SD, Pfaff DW (1991) Expression of a functional foreign gene in adult mammalian brain following in Vivo transfer via a herpes simplex virus type 1 defective viral vector. Mol Cell Neurosci 2:320-330. [PubMed] [Content]
Pfaus JG, Damsma G, Nomikos GG, Wenkstern DG, Blaha CD, Phillips AG, Fibiger HC (1990) Sexual behavior enhances central dopamine transmission in the male rat. Brain Res 530:345-348. [PubMed] [Content]
Pfaus JG, Mendelson SD, Phillips AG (1990) A correlational and factor analysis of anticipatory and consummatory measures of sexual behavior in the male rat. Psychoneuroendocrinology 15:329-340. [PubMed] [Content]
Pfaus JG, Phillips AG (1989) Differential effects of dopamine receptor antagonists on the sexual behavior of male rats. Psychopharmacology (Berl) 98:363-368. [PubMed] [Content]Pfaus JG, Pinel JPJ (1989) Alcohol inhibits and disinhibits sexual behavior in the male rat. Psychobiol 17:195-201. [Content]
Paul D, Mana MJ, Pfaus JG, Pinel JP (1988) Attenuation of morphine analgesia by the S2 antagonists, pirenperone and ketanserin. Pharmacol Biochem Behav 31:641-647. [PubMed] [Content]Pfaus JG, Blackburn JR, Harpur TJ, MacDonald M, Mana MJ, Jacobs WJ (1988) Has psychology ever been a science of behavior? A comment on Skinner. American Psychologist 43:821-822. [Content]
Blackburn JR, Pfaus JG (1988) Is motivation really modulation? A comment on Wise. Psychobiol 16:303-304. [Content]Jacobs WJ, Blackburn JR, Buttrick M, Harpur TJ, Kennedy D, Mana MJ, MacDonald MA, McPhereson L, Paul D, Pfaus JG (1988) Observations. Psychobiol 16:3-19. [Content]
Pfaus JG, Pendleton N, Gorzalka BB (1986) Dual effect of morphiceptin on lordosis behavior: possible mediation by different opioid receptor subtypes. Pharmacol Biochem Behav 24:1461-1464. [PubMed] [Content]
Pfaus, JG (2015). Sexuality and pleasure are phylogenetically linked and conserved. In Sexual Health and Sexual Ecology (Pp. 13-17). MilanoL IBSA foundation.
Pfaus, JG, Jones, SL, Flanagan-Cato, L, & Blaustein, JD (2014). Chapter 50: Female sexual behavior. In Plant, A.M., Zeleznik, A.J. (Eds.), Knobil & Neill’s Physiology of Reproduction, Fourth Edition, (Pp. 2287-2370). New York: Elsevier.
Pfaus, JG, Scepkowski, LA, Marson, L., & Georgiadis, J. (2013). Biology of the sexual response. In Tolman, DL & Diamond, LM (Eds.), APA Handbook of Sexuality and Psychology (Pp. 143-203). Washington DC: APA Press.
Coria-Avila, GA, & Pfaus, JG (2012). Conducta sexual. In Coria-Avila, GA, (Ed.), Neurofisiología de la Conducta (pp. 184-201). Xalapa, VER, México: Universidad Veracruzana Press.
Pfaus, J.G. (2011). Physiology of libido. In Mulhall, J., Goldstein, I., Incrocci, L., & Rosen, R. (Eds.), Cancer and Sexuality (pp. 25-34). New York: Humana Press.
Rowland DL, Pfaus JG (2009) Sexual development: Physiological development. In: Dixon S (Ed.) The Chicago Companion to the Child. Chicago, IL: University of Chicago Press.
Pfaus JG (2007) Models of sexual motivation. In: Janssen E (Ed.) The Psychophysiology of Sex, pp. 340-362. Indiana U. Press.
Giuliano F, McKenna K, Srilatha B, Pfaus JG (2006) Preclinical research and animal models in sexual medicine. In: Porst H, Buvat J (Eds.) Standard Practice in Sexual Medicine, pp. 1-17. London: Blackwell. [DOI] [Content]
Scepkowski LA, Georgescu M, Pfaus JG (2006) Neuroendocrine factors in sexual desire and motivation. In: Goldstein I, Meston C, Davis K, Traish A (Eds.) Women's Sexual Function and Dysfunction (pp. 159-167). London: Taylor and Francis. [PDF]
Goldstein I, Giraldi A, Kodigliu A, van Lunsen HW, Marson L, Nappi R, Pfaus JG, Salonia A, Traish A, Vardi Y (2004) Physiology of female sexual function and pathophysiology of female sexual dysfunction. In: Khoury S (Ed.) Sexual Medicine: Sexual Dysfunctions in Men and Women (pp. 683-747). WHO Press, Paris.
Pfaus JG (2002) Sexual differentiation of sexual behavior. In: International Symposium on Environmental Endocrine Disruptors. Tokyo, Nippon Press. [PDF]
Pfaus JG (2001) Contributions to the Dictionary of Biological Psychology. Winn P (Ed.) London: Routledge.
Pfaus JG (1997) Sexy GnRH neurons. In: Parhar IS, Sakuma Y (Eds.) GnRH neurons: Gene to behavior (pp. 367-388). Tokyo: Brain Shuppan Publishers.
Pfaus JG (1995) Neural mechanisms of sexual motivation and performance in females. In Bancroft J (Ed.) The pharmacology of sexual function and dysfunction (pp. 37-48). Amsterdam: Elsevier.
Pfaus JG, Everitt BJ (1995) The psychopharmacology of sexual behavior. In Bloom FE, Kupfer DJ (Eds) Psychopharmacology: The fourth generation of progress (pp. 743-758). New York: Raven Press.
Phillips AG, Blaha CD, Pfaus JG, Blackburn JR (1992) Neurobiological correlates of positive emotional states: Dopamine, anticipation, and reward. In: Strongman K (Ed.) International review of studies on emotion, Vol. 2 (pp. 31-50). Chichester: Wiley.
Phillips AG, Pfaus JG, Blaha CD (1991) Dopamine and motivated behavior: Insights provided by in vivo analyses. In: Willner P, Scheel-Kruger J (Eds.) The mesolimbic dopamine system: From motivation to action (pp. 199-224). London: Wiley.
Pfaus JG, Pinel JPJ (1990) Alcohol inhibits and disinhibits sexual behavior. In: Pinel JPJ (Ed.) Current research in biopsychology (pp. 211-219). Boston: Allyn & Bacon.
Pfaus JG, Pinel JPJ, Christensen BK (1988) Effects of alcohol on the sexual behavior of male rats: Disruption, disinhibition, and tolerance. In: Kuriyama K, Takada A, Ishii H (Eds.) Biomedical aspects of alcohol and alcoholism (pp.443-446). Amsterdam: Elsevier.
Jim Pfaus received his Ph.D. in Psychology from the University of British Columbia in 1990 under the direction of Drs. Anthony G. Phillips and H. Christian Fibiger. Following postdoctoral training in molecular biology and behavior with Dr. Donald Pfaff at the Rockefeller University (1990-1992), he joined the Department of Psychology and the Center for Studies in Behavioral Neurobiology at Concordia University where he is a full professor. Jim was the 1995 recipient of the Frank A. Beach Award from the Society for Behavioral Neuroendocrinology, and in 1997 was inducted into the International Academy of Sex Research. He received the Frank A. Beach Comparative Psychology Award from the American Psychological Association in 2009, the Sandra Lieblum Lectureship from the International Society for Sexual Medicine in 2011, the Herbert Thomas Award from the American Society for Reproductive Medicine in 2012, the Concordia University Research Award in 2013, and the Distinguished Scientist Award from the Society for the Scientific Study of Sexuality in 2014. He was made a fellow (IF) of the International Society for the Study of Women’s Sexual Health (ISSWSH) and a Concordia Research Fellow, both in 2013. Jim is the current President of the International Academy of Sex Research (IASR), serves on the Standards Committee of the International Society for Sexual Medicine (ISSM), and on the Board of Directors of ISSWSH. Jim is an associate editor of the Journal of Sexual Medicine and Sexual Medicine Reviews, section editor for preclinical research and psychophysiology for Current Sexual Health Reports, and serves on the editorial boards of the Behavioral Neuroscience, Hormones and Behavior, Investigative and Clinical Urology, and Physiology and Behavior. He is also an associate editor of the APA Handbook of Psychology and Sexuality. At Concordia, Jim serves as Chair of the Human Research Ethics Committee, Vice-Chair of the Animal Research Ethics Committee, and is a Fellow of Concordia’s Science College. He is cross-appointed in the graduate programs of Biology, Chemistry and Biochemistry, and Exercise Science.
Jim’s son Josh (age 13) is an amazing violin and hockey player.
Former Postdoctoral Fellows
Tina Scardochio, PhD (Clinical Research Director, Celerion Applied Translational Medicine, Montréal, QC)
Shavindra Dias, MD (Department of Medicine, University of Columbo, Sri Lanka)
Sarah Farrell, PhD (Research Scientist, Department of Physiology, University of Rochester, Rochester, NY)
Hélène Gelez, PhD (Senior Research Scientist, Pelvipharm SAS, Gif-sur-Yvette, Paris, France)
Paul Vasey, PhD (Professor, Department of Psychology, University of Lethbridge, Lethbridge, AB)
Carol Coopersmith, PhD (Senior Research Associate, Department of Biological Sciences, University of California Irvine, Irvine, CA)
Former Graduate Students
Sherrie Lee Jones, PhD (Behavioral Neuroscience, 2015). Current postion: PDF, Douglas Research Hospital, Department of Psychiatry, McGill University, Montréal, QC.
Amanda Holley, PhD (Biology, 2015). Current position: PDF, Section for IntegrativeBiology, Division of Biological Sciences, University of Texas at Austin,Austin, TX.
Tonje Persson, PhD (Clinical Psychology, 2014). Current position: Clinical psychologist in private practice, Montréal, QC.
Mayte Parada, PhD (Behavioral Neuroscience, 2013). Current position: PDF, Department of Psychology and Montreal Neurological Institute, McGill University, Montréal, QC.
Michaela Georgescu, PhD (Clinical Psychology, 2010). Current position: Clinical psychologist in private practice, Hudson, QC.
Bita Sharifzadeh, PhD (Clinical Psychology, 2009). Current position: Clinical psychologist in private practice, Montréal, QC.
Nafissa Ismail, PhD (Behavioral Neuroscience, 2008). Current position: Assistant Professor, Department of Psychology, University of Ottawa, Ottawa, ON.
Veronica Afonso, PhD (Behavioral Neuroscience, 2007). Current position: Student Learning Coordinator, Math and Science, Nipissing University, North Bay, ON.
Genaro A. Coria-Avila, DVM, PhD (Behavioral Neuroscience, 2007). Current position: Investigador Titular, Instituto de Neurobiología, Universidad Veracruzana, Xalapa, VER, México.
Wendy Smith, PhD (Clinical Psychology, 2006). Current position: Clinical psychologist in private practice, Pointe Claire, QC.
Rachel Toledano, PhD (Clinical Psychology, 2006). Current position: Clinical psychologist in private practice, Montréal, QC.
Soraya Centeno, PhD (Behavioral Neuroscience, 2002). Current position: Director of Investor Relations at Transition Therapeutics, Toronto, ON.
Tod Kippin, PhD (Behavioral Neuroscience, 2000). Current position: Associate Professor, Psychological and Brain Sciences, Neuroscience Research Institute, University of California Santa Barbara, Santa Barbara, CA.
James Cantor, PhD (Clinical Psychology, McGill, 1999). Current position: Associate Professor, Department of Psychiatry, University of Toronto, Toronto, ON.