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Workshops & seminars

"Recreating complex biochemical mechanisms using DNA switches: from fundamentals to applications in bio-nanotechnology"
Dr. Alexis Vallee-Belisle (Universite de Montreal)


Date & time
Friday, March 6, 2015
2:30 p.m. – 3:30 p.m.
Speaker(s)

Dr. Alexis Vallee-Belisle

Cost

This event is free

Website

Contact

Dajana Vuckovic

Where

Richard J. Renaud Science Complex
7141 Sherbrooke W.
Room SP-S110

Wheel chair accessible

Yes

Nature has evolved countless finely regulated biomolecules and nanomachines that display amazingly complex and efficient mechanisms. In my talk, I will describe how we are gaining a better understanding of those sophisticated mechanisms by recreating them in vitro, using simple DNA switches. Inspired by this exercise, we are now developing various bio-inspired nano-devices that respond to specific chemical or environmental changes that prove of utility for several applications in the fields of in vivo imaging, clinical diagnostics, and drug-delivery. In my talk, I will describe how we develop and optimise programmable structure-switching DNA devices that use fluorescent or electrochemical readouts to measure temperature, pH, or molecules, from small-sized drugs to larger transcription factors and antibodies present in cellular extract or whole blood samples.

Dr. Vallee-Belisle is the guest of Prof. Joanne Turnbull

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