Circadian rhythms and sleep are fundamental processes that impact all levels of physiological organization from gene expression, protein synthesis, biochemical pathways, to coordination of the function of tissues, organs, organ systems, and whole-body physiology and behavior. This talk will highlight mechanisms by which circadian misalignment and sleep disruption dysregulate human physiology, including the human microbiome, with implications for human health and disease.
Following this talk, participants will:
Be able to describe how insufficient sleep and circadian misalignment disrupt glucose metabolism
Understand how circadian misalignment impacts the human proteome with consequences for metabolic function
Learn how combined circadian misalignment and sleep loss impact the structure and function of the human microbiome
Ken Wright is College Professor of Distinction in the Department of Integrative Physiology and the Director of the Sleep and Chronobiology Laboratory at the University of Colorado Boulder.