Sleep and circadian disruption are common in older Canadians. This talk will review some of our work examining some of the brain correlates of sleep and circadian disruption in aging, and their association with incident cognitive decline and dementia.
At the end of the presentation participants will be able to:
• Understand approaches to assessing sleep and circadian disruption using wearable devices
• Describe imaging and pathological brain correlates of sleep fragmentation in older persons
• Describe associations, between sleep fragmentation, genetic background, and incident cognitive decline and dementia in older persons
Dr. Lim completed his medical degree and residency in neurology at the University of Toronto, and a fellowship in sleep and circadian biology with Dr. Clifford Saper at the Beth Israel Deaconess Medical Center in Boston. His research is focused on understanding the links between our genes, sleep and circadian biology, and neurological diseases in aging.
Financial Support and Conflict of Interest Disclosures
Dr. Lim has served as a consultant for UCB Pharma Inc and Merck & Co Inc. He has received research support from ResMed Inc. and Phillips-Respironics Inc. He was the recipient of a Clinical Research Training Fellowship from the American Brain Foundation and a Bisby Felllowship from the CIHR. He receives support from CIHR grants MOP125934 (PI) MOP336806 (co-PI) MSH136642 (PI) and MMC112692 (PI), Heart and Stroke Foundation of Ontario bridge grant 7487 (PI), and NIH Grants R01NS0700902 (consultant) R01AG051175 (Co-I) and R01AG048108 (consultant)