Discuss age-related changes in skeletal muscle mitochondrial function
Discuss role of different modes and intensities of exercise to optimize mitochondrial function
Brian A. Irving, PhD is an Assistant Professor in the School of Kinesiology at Louisiana State University and an Adjunct Assistant Professor at Pennington Biomedical Research Center. He received his B.S. in Exercise and Sports Sciences from Oregon State University in 2000. He also received his M.S. in Health Evaluation Sciences in 2004, and his PhD in Exercise Physiology in 2006 from the University of Virginia (UVa). The focus of his doctoral training at UVa was on exercise physiology, body composition, endocrinology and metabolism, and clinical trials methodologies in individuals with and without cardiometabolic diseases. Subsequently, he received postdoctoral training in endocrinology and metabolism and mentored career development in clinical and translational sciences at the Mayo Clinic, MN. The focus of his postdoctoral training and mentored career development programs was on skeletal muscle protein synthesis, mitochondrial function, and cardiometabolic adaptations to exercise in young and older adults with and without cardiometabolic diseases (e.g., sarcopenia, diabetes). Finally, prior to joining LSU, Dr. Irving served as a staff scientist at Geisinger Medical Center’s Obesity Institute and was the founding director of its Metabolic Phenotyping Unit.
Dr. Irving’s laboratory is interested in developing a more thorough understanding of the short- and long-term metabolic and proteomic adaptions to exercise, diet, and medical interventions in young and old adults with and without cardiometabolic diseases. Specifically, his laboratory is interested in skeletal muscle adaptations that provide protection against cardiometabolic diseases (e.g., type 2 diabetes, cardiovascular disease, and peripheral vascular disease). His laboratory also studies the effects that sedentary behaviors have on skeletal muscle and whole-body physiology. Finally, his laboratory is interested identifying mechanisms of exercise intolerance and functional impairment in overweight/obese older adults. He currently serves as a direction of physical function testing for a multi-center clinical trial on the impact of bariatric surgery prior to patients undergoing total knee replacement. Dr. Irving has received research support from the National Institutes of Health, and United States Department of Agriculture.