ABSTRACT: Imaging is a fundamental tool in the practice of medicine. In parallel with the development of improved imaging systems and techniques, there is increasing interest in designing new contrast agents that can help guide and assess personalized treatment for cancer patients. A new opportunity in materials science is the development of new injectable materials that can be triggered by medical imaging radiation under image guidance to deliver drugs to disease sites in situ. Specific examples of different composite contrast agents that are assembled to address and balance biological and physical challenges of contrast agent development will be given, with a focus on the use of perfluorocarbon bubbles and droplets as multifunctional contrast agents for ultrasound imaging and therapy applications.
BIO: Naomi Matsuura, PhD, P.Eng, is an Associate Professor in the Department of Materials Science and Engineering / IBBME, cross-appointed to the Department of Medical Imaging, at the University of Toronto. Dr. Matsuura received her BASc and MASc in Engineering Physics from Queen’s University and a PhD from the University of Toronto in Materials Science in Engineering. Dr. Matsuura leads a research program based on the design of new, translatable contrast agents to guide the personalized treatment of cancer. Awards and recognitions include the John C. Polanyi Prize in Physiology/Medicine and Physics, an NSERC Discovery Accelerator Award, and the Early Researcher Award from the Ontario Ministry of Research and Innovation.