Seeing and Building Tumours: The Role of Advanced Materials in Oncology
Dr. Matt Kinsella(McGill University)
Abstract: Cancer diagnoses, and increasingly treatment options, are increasingly being aided by the development of new molecular imaging technologies. Central to the utility of these procedures has been the concurrent development of contrast agents that enable clinicians to clearly delineate tumor peripheries, determine pathologies, and develop personalized intervention strategies. One of the critical challenges faced in cancer bioengineering is the translation of compounds, including NPs, from the current small animal models, and cellular screening tools, to patients. This seminar will address tumor tissue-specific nanoparticles we’ve developed as potential microCT and PET contrast agents for the direct in vivo detection of solid tumors. And our more recent efforts developing novel materials, and methodologies, to explore bioprinting strategies to create new tumor models enabling more predictive clinical translation of therapeutics from in vitro and preclinical small animal in vivo platforms.
Bio: Matt Kinsella is an Assistant Professor of Bioengineering at McGill University in Montreal, QC, Canada. Before joining the faculty at McGill in 2012 he was an American Cancer Society Postdoctoral Fellow at the University of California, San Diego. His postdoctoral research, in the Sailor lab at UCSD and in collaboration with the Ruoslahti lab at SBMRI, focused on developing nanomaterials to aid in medical imaging. In 2007 he received his PhD from the Weldon School of Biomedical Engineering at Purdue University working with Prof Albena Ivanisevic.
Dr. Kinsella is the guest of Dr. Rafik Naccache.